NDST2

Gene Symbol NDST2
Entrez Gene 8509
Alt Symbol HSST2, NST2
Species Human
Gene Type protein-coding
Description N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
Other Description N-HSST 2|N-heparan sulfate sulfotransferase 2|NDST-2|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2|glucosaminyl N-deacetylase/N-sulfotransferase 2
Swissprots Q59H89 Q2TB32 P52849
Accessions AAB97086 EAW54525 EAW54526 P52849 AB208870 BAD92107 AK293527 BAG57009 AK298957 BAG61053 AK300520 BAG62232 AK301251 BAG62818 AK303648 BAG64651 AK310580 BC018681 BC035711 AAH35711 BC110588 AAI10589 BC110589 AAI10590 U36601 AAC27120 XM_005270255 XP_005270312 XM_005270256 XP_005270313 XM_006718046 XP_006718109 XM_011540310 XP_011538612 XR_945852 NM_003635 NP_003626
Function Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. {ECO:0000269|PubMed:10758005, ECO:0000269|PubMed:12634318, ECO:0000269|PubMed:16343444}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

NDST2 CRISPR/Cas9 KO Plasmid (h) - sc-409718 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 HDR Plasmid (h) - sc-409718-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 Double Nickase Plasmid (h) - sc-409718-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 Double Nickase Plasmid (h2) - sc-409718-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 CRISPR Activation Plasmid (h) - sc-409718-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 CRISPR Activation Plasmid (h2) - sc-409718-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 Lentiviral Activation Particles (h) - sc-409718-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 Lentiviral Activation Particles (h2) - sc-409718-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDST2 siRNA (h) - sc-40763 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDST2 shRNA Plasmid (h) - sc-40763-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDST2 shRNA (h) Lentiviral Particles - sc-40763-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU156301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15131 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15131 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04548 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04548

NDST2 siRNA (Human) - CRH5583 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NDST2 (NM_003635.3) - SHH350424 from Creative biogene

Category siRNA
Species Reactivities Human

Human NDST2 siRNA - orb266085 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NDST2 shRNA Plasmid (Human) - CHH5583 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NDST2 miRNA 3'UTR clone - MiUTR3H-05827 from Creative biogene

Species Reactivities Human
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