CPE

Gene Symbol	CPE
Entrez Gene	1363
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	carboxypeptidase E
Other Description	CPH|carboxypeptidase H|cobalt-stimulated chromaffin granule carboxypeptidase|enkephalin convertase|insulin granule-associated carboxypeptidase|prohormone-processing carboxypeptidase
Swissprots	Q9UIU9 P16870 D3DP33 A8K4N1 B4DFN4 B3KR42
Accessions	BAA86053 EAX04817 EAX04818 EAX04819 P16870 AI340177 AK090962 BAG52254 AK127165 BAG54445 AK290996 BAF83685 AK294175 BAG57495 BC033866 AAH33866 BC053612 AAH53612 BM271829 DQ893322 ABM84248 DQ896637 ABM87636 X51405 CAA35767 NM_001873 NP_001864
Function	Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.
Subcellular Location	Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions. {ECO:0000250}.
Tissue Specificity	Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas. {ECO:0000269|PubMed:21285511}.
Top Pathways	Type I diabetes mellitus

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CPE / Carboxypeptidase E ELISA Kit (Sandwich ELISA) - LS-F6583 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.238 ng/ml Range 0.625-40 ng/ml

Human Carboxypeptidase E ELISA Kit - abx150934 from Abbexa Category ELISA Kit Sensitivity 0.238 ng/ml Range 0.625 ng/ml - 40 ng/ml

Carboxypeptidase E (CPE), Human, ELISA Kit - CSB-EL005886HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 9.76 pg/ml Range 39.06 pg/ml-2500 pg/ml

Carboxypeptidase E (CPE), Human, ELISA Kit - SEF322Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.238ng/mL Range 0.625-40ng/mL

Carboxypeptidase E (CPE), Human, ELISA Kit - E01C1997 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Carboxypeptidase E, CPE, Human, ELISA Kit - E-EL-H0351 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.375 Range 0.625-40ng/mL

Carboxypeptidase E, CPE, Rabbit, ELISA Kit - E-EL-RB2234 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Carboxypeptidase E, CPE, Chicken, ELISA Kit - E-EL-Ch0680 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Carboxypeptidase E, CPE, Porcine, ELISA Kit - E-EL-P1341 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Carboxypeptidase E, CPE, Sheep, ELISA Kit - E-EL-S0265 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Carboxypeptidase E, CPE, Monkey, ELISA Kit - E-EL-MK2017 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Carboxypeptidase E, ELISA Kit - MBS071079 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E, ELISA Kit - MBS084405 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

carboxypeptidase E, ELISA Kit - MBS944061 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.76 pg/ml Range 39.06 pg/ml-2500 pg/ml

Carboxypeptidase E, ELISA Kit - MBS060912 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7229954 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7224335 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7228244 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7245416 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7206770 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS2023838 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of CPE is typically less than 0.238ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.625-40ng/mL

Carboxypeptidase E (CPE), ELISA Kit - MBS7215792 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7246280 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7229132 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxypeptidase E (CPE), ELISA Kit - MBS7230929 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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