CPE

Gene Symbol	CPE
Entrez Gene	1363
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	carboxypeptidase E
Other Description	CPH|carboxypeptidase H|cobalt-stimulated chromaffin granule carboxypeptidase|enkephalin convertase|insulin granule-associated carboxypeptidase|prohormone-processing carboxypeptidase
Swissprots	Q9UIU9 P16870 D3DP33 A8K4N1 B4DFN4 B3KR42
Accessions	BAA86053 EAX04817 EAX04818 EAX04819 P16870 AI340177 AK090962 BAG52254 AK127165 BAG54445 AK290996 BAF83685 AK294175 BAG57495 BC033866 AAH33866 BC053612 AAH53612 BM271829 DQ893322 ABM84248 DQ896637 ABM87636 X51405 CAA35767 NM_001873 NP_001864
Function	Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.
Subcellular Location	Isoform 1: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions. {ECO:0000250}.
Tissue Specificity	Isoform 2, but not isoform 1, is overexpressed in hepatocellular carcinoma (at protein level), as well as in other tumors, including pheochromocytomas and paragangliomas. {ECO:0000269|PubMed:21285511}.
Top Pathways	Type I diabetes mellitus

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CPE-cDNA-Clone - DC06678 from Abgent, a WuXi AppTec company Prices $642.60 Sizes 10 µg Species Human Accession BC033866

CPE - MBS1275512 from MyBioSource Species Human Accession BC033866

Human CPE ORF Clone(NM_001873.2) - CDCL159595 from Creative Biomart Species Human Accession NM_001873.2

Human CPE ORF clone(NM_001873.2) - CDCL183700 from Creative Biomart Species Human Accession NM_001873.2

Human Carboxypeptidase E/CPE Gene ORF cDNA clone in cloning vector - HG10069-M from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, C-HA tag - HG10069-CY from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid - HG10069-UT from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, C-His tag - HG10069-CH from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, N-HA tag - HG10069-NY from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10069-NF from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10069-CF from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10069-ACG from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10069-M-F from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10069-NM from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid - HG10069-M-N from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10069-CM from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, N-His tag - HG10069-NH from Sino Biological Species Human

Human Carboxypeptidase E/CPE Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10069-ACR from Sino Biological Species Human

Human CPE ORF clone(NM_001873.2) - CDCL183700 from Creative biogene Species Human

Human CPE ORF Clone (BC033866) - CDCS410491 from Creative biogene Species Human Accession P16870

Human CPE gene - orb90687 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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