OMA1

Gene Symbol OMA1
Entrez Gene 115209
Alt Symbol 2010001O09Rik, DAB1, MPRP-1, YKR087C, ZMPOMA1, peptidase
Species Human
Gene Type protein-coding
Description OMA1 zinc metallopeptidase
Other Description OMA1 homolog, zinc metallopeptidase|OMA1 zinc metallopeptidase homolog|metalloendopeptidase OMA1, mitochondrial|metalloprotease related protein 1|metalloprotease-related protein 1|overlapping activity with M-AAA protease|overlapping with the m-AAA protease 1 homolog|zinc metallopeptidase OMA1
Swissprots Q5T3G8 Q96E52 Q5T3G6 D3DQ54 Q8NBB3 Q5T3H0 Q5T3G9 Q5T3G7
Accessions CAE48420 EAX06631 EAX06632 EAX06633 EAX06634 Q96E52 AB048348 BAC79381 AK091101 BAC03583 AK308847 BC012915 AAH12915 BU191827 JF432270 ADZ15487 NM_145243 NP_660286
Function Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. {ECO:0000269|PubMed:20038677}.
Subcellular Location Mitochondrion inner membrane {ECO:0000305|PubMed:20038677}; Multi-pass membrane protein {ECO:0000305|PubMed:20038677}.
Tissue Specificity Widely expressed, with strong expression in the heart, skeletal muscle, kidney and liver. {ECO:0000269|PubMed:12886954}.

Oma1 (N-14) - sc-168843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Oma1 (P-19) - sc-168844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Oma1 (P-19): sc-168844. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing apical membrane and cytoplasmic staining of cells in tubules.

Anti-OMA1 antibody - ab154949 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of OMA1 staining in human normal kidney formalin fixed paraffin embedded tissue section*, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab154949, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.*Tissue obtained from the Human Research Tissue Bank, supported by the NIHR Cambridge Biomedical Research Centre

Anti-OMA1 antibody - C-terminal - ab185532 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling OMA1 with ab185532 at 1/500 dilution.

Anti-OMA1 Antibody (aa359-408) - LS-C116519 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
OMA1 antibody LS-C116519 Western blot of 721_B cell lysate.

OMA1 Antibody - NBP1-56970 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

DAB1 Antibody - NBP1-19883 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DAB1 Antibody [NBP1-19883] - DAB1 Antibody extracts from HeLa cells.

OMA1 Antibody - NBP2-30971 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dab1 Polyclonal Antibody - bs-11547R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dab1 (Tyr198) Polyclonal Antibody - bs-11548R from Bioss

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-Phospho-Dab1 (Tyr198)Polyclonal Antibody, Unconjugated (bs-11548R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Rabbit Anti-Dab1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11547R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11547R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11547R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, Cy3 Conjugated - bs-11547R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, Cy5 Conjugated - bs-11547R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, Cy5.5 Conjugated - bs-11547R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, Cy7 Conjugated - bs-11547R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, FITC Conjugated - bs-11547R-FITC from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, Biotin Conjugated - bs-11547R-Biotin from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Dab1 Polyclonal Antibody, HRP Conjugated - bs-11547R-HRP from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dab1 (Tyr198) Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11548R-A350 from Bioss

Prices $389.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dab1 (Tyr198) Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11548R-A488 from Bioss

Prices $389.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dab1 (Tyr198) Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11548R-A555 from Bioss

Prices $389.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dab1 (Tyr198) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11548R-A647 from Bioss

Prices $389.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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