OMA1

Gene Symbol OMA1
Entrez Gene 115209
Alt Symbol 2010001O09Rik, DAB1, MPRP-1, YKR087C, ZMPOMA1, peptidase
Species Human
Gene Type protein-coding
Description OMA1 zinc metallopeptidase
Other Description OMA1 homolog, zinc metallopeptidase|OMA1 zinc metallopeptidase homolog|metalloendopeptidase OMA1, mitochondrial|metalloprotease related protein 1|metalloprotease-related protein 1|overlapping activity with M-AAA protease|overlapping with the m-AAA protease 1 homolog|zinc metallopeptidase OMA1
Swissprots Q5T3G8 Q96E52 Q5T3G6 D3DQ54 Q8NBB3 Q5T3H0 Q5T3G9 Q5T3G7
Accessions CAE48420 EAX06631 EAX06632 EAX06633 EAX06634 Q96E52 AB048348 BAC79381 AK091101 BAC03583 AK308847 BC012915 AAH12915 BU191827 JF432270 ADZ15487 NM_145243 NP_660286
Function Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. {ECO:0000269|PubMed:20038677}.
Subcellular Location Mitochondrion inner membrane {ECO:0000305|PubMed:20038677}; Multi-pass membrane protein {ECO:0000305|PubMed:20038677}.
Tissue Specificity Widely expressed, with strong expression in the heart, skeletal muscle, kidney and liver. {ECO:0000269|PubMed:12886954}.

Oma1 CRISPR/Cas9 KO Plasmid (h) - sc-402953 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 HDR Plasmid (h) - sc-402953-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 Double Nickase Plasmid (h) - sc-402953-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 Double Nickase Plasmid (h2) - sc-402953-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 CRISPR Activation Plasmid (h) - sc-402953-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 CRISPR Activation Plasmid (h2) - sc-402953-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 Lentiviral Activation Particles (h) - sc-402953-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 Lentiviral Activation Particles (h2) - sc-402953-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Oma1 siRNA (h) - sc-78998 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Oma1 shRNA Plasmid (h) - sc-78998-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Oma1 shRNA (h) Lentiviral Particles - sc-78998-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU072451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15726 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15726 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

OMA1 siRNA (Human) - CRJ4435 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human OMA1 (NM_145243.3) - SHH366452 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human OMA1(NM_145243.3) - SHG220825 from Creative biogene

Category siRNA
Species Reactivities Human

Human OMA1 siRNA - orb274936 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

OMA1 shRNA Plasmid (Human) - CHJ4435 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

OMA1 miRNA 3'UTR clone - MiUTR1H-07059 from Creative biogene

Species Reactivities Human
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