OMA1

Gene Symbol	OMA1
Entrez Gene	115209
Alt Symbol	2010001O09Rik, DAB1, MPRP-1, YKR087C, ZMPOMA1, peptidase
Species	Human
Gene Type	protein-coding
Description	OMA1 zinc metallopeptidase
Other Description	OMA1 homolog, zinc metallopeptidase|OMA1 zinc metallopeptidase homolog|metalloendopeptidase OMA1, mitochondrial|metalloprotease related protein 1|metalloprotease-related protein 1|overlapping activity with M-AAA protease|overlapping with the m-AAA protease 1 homolog|zinc metallopeptidase OMA1
Swissprots	Q5T3G8 Q96E52 Q5T3G6 D3DQ54 Q8NBB3 Q5T3H0 Q5T3G9 Q5T3G7
Accessions	CAE48420 EAX06631 EAX06632 EAX06633 EAX06634 Q96E52 AB048348 BAC79381 AK091101 BAC03583 AK308847 BC012915 AAH12915 BU191827 JF432270 ADZ15487 NM_145243 NP_660286
Function	Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions. {ECO:0000269|PubMed:20038677}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000305|PubMed:20038677}; Multi-pass membrane protein {ECO:0000305|PubMed:20038677}.
Tissue Specificity	Widely expressed, with strong expression in the heart, skeletal muscle, kidney and liver. {ECO:0000269|PubMed:12886954}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OMA1 full length protein - ab153578 from Abcam Category Protein Source Wheat germ Species Human

OMA1 peptide - ab129125 from Abcam Category Peptide

DAB1 Antibody Blocking Peptide - LS-E18839 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DAB1 Antibody Blocking Peptide - LS-E9885 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OMA1 Antibody Blocking Peptide - LS-E19033 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human OMA1 Protein - H00115209-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human DAB1 Protein - H00001600-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DAB1 Blocking Peptide - 33R-7396 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

OMA1 Blocking Peptide - 33R-9932 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DAB1 Blocking Peptide - abx062523 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Monkey, Pig

OMA1 / MPRP1 - H00115209-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

OMA1 fusion protein - Ag11201 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

OMA1 fusion protein - Ag10803 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human OMA1, His-tagged - OMA1-1456H from Creative Biomart Category Protein Source E.coli Species Human

DAB1 Recombinant Protein Antigen - NBP2-38661PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DAB1 Peptide, Human - M34GP04005H from Creative Peptides Category Peptide Source Synthetic. Species Human

OMA1 Peptide, Human - M34GP10842H from Creative Peptides Category Peptide Source Synthetic. Species Human

OMA1 Recombinant Protein Antigen - NBP2-30971PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

human OMA1 protein - orb54682 from Biorbyt Category Protein Prices $1,972.00, $3,468.00, $5,338.00 Sizes 10 μg, 50 μg, 100 μg Species Human

DAB1 Recombinant Protein Antigen - NBP2-57001PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Metalloendopeptidase OMA1 (OMA1), Recombinant Protein - MBS7024476 from MyBioSource Category Protein Prices $1,160.00, $1,665.00, $2,570.00 Sizes 10 µg, 50 µg, 100 µg Source In vitro E Coli Species Human

OMA1 Recombinant Protein (Human) (OPCA05302) - OPCA05302 from Aviva Systems Biology Category Protein Species Human

Recombinant Human OMA1 Protein, GST-tagged - OMA1-1457H from Creative Biomart Category Protein Source Wheat Germ Species Human

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