IL11RA

Gene Symbol	IL11RA
Entrez Gene	3590
Alt Symbol	CRSDA
Species	Human
Gene Type	protein-coding
Description	interleukin 11 receptor, alpha
Other Description	IL-11 receptor subunit alpha|IL-11R subunit alpha|interleukin-11 receptor alpha chain|interleukin-11 receptor subunit alpha
Swissprots	Q5VZ80 Q14626 Q7KYJ7 Q16542
Accessions	AAB36491 AAS00093 EAW58422 EAW58423 EAW58424 EAW58425 Q14626 AI377039 AK075530 AK094689 BAG52913 AK292073 BAF84762 BC003110 AAH03110 BT009864 AAP88866 DA917660 DC424068 DQ892342 ABM83268 DQ895548 ABM86474 U32324 AAB36492 Z38102 CAA86224 Z46595 CAA86570 NM_001142784 NP_001136256 NR_052010 NM_004512 NM_147162
Function	Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number. {ECO:0000269|PubMed:21741611}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, the megakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63 and SaOS-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma. {ECO:0000269|PubMed:11141475}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL11RA full length protein - ab132575 from Abcam Category Protein Source Wheat germ Species Human

Human IL11RA protein fragment - ab127328 from Abcam Category Protein Source E. coli Species Human

IL11RA Antibody Blocking Peptide - LS-E16938 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IL11RA Antibody Blocking Peptide - LS-E16939 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IL11RA Protein - H00003590-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human IL-11 R alpha Fc Chimera, CF - 1977-MR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Canine IL11RA protein - orb139103 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

Canine IL11RA (Fc Tag) protein - orb232677 from Biorbyt Category Protein Prices $434.00, $816.00 Sizes 50 μg, 200 μg

Human IL11Ra Protein - abx067431 from Abbexa Category Protein Source E.coli Species Human

IL11RA - H00003590-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IL11RA - H00003590-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

IL11RA fusion protein - Ag0373 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Recombinant Human IL11RA, His tagged - IL11RA-3155H from Creative Biomart Category Protein Source Human Cells Species Human

Human IL-11 receptor alpha Recombinant - RKQ14626 from Reprokine Category Protein Prices $160.00, $480.00, $1,950.00 Sizes 20 µg, 100 µg, 500 µg Source DNA sequence encoding extracellular domain of human IL-11RA fused to a C-terminal polyHis tag was expressed in HEK cells. Species Human

Recombinant Interleukin 11 Receptor Alpha (IL11Ra) - RPE771Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Interleukin 11 Receptor Alpha (IL11Ra) - RPE771Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Interleukin 11 Receptor Alpha (IL11Ra) - RPE771Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Interleukin 11 Receptor Alpha (IL11Ra) - RPE771Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Human IL11RA / IL11Rα Protein (His Tag) - 10252-H08H-50 from Sino Biological Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

IL-11Rα (D361) Peptide - BS9265P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Interleukin-11 receptor subunit alpha(IL11RA) - CSB-YP623927HU CSB-EP623927HU CSB-BP623927HU CSB-MP623927HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human IL-11 R alpha Protein, CF - 8895-MR from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Ser24-Val363, with a C-terminal 6-His tag Species Human

Recombinant Human IL-11 R alpha Fc Chimera Protein, CF - 1977-MR from R&D Systems Category Protein Prices $339.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human IL-11 R alpha (Cys26 - Val363) Accession # Q5VZ80 IEGRMD Human IgG 1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus Species Human

IL11RA Protein - abx163773 from Abbexa Category Protein Species Human

IL11RA Protein - abx163360 from Abbexa Category Protein Species Human, Mouse, Rat

Search more