ZRANB1

Gene Symbol	ZRANB1
Entrez Gene	54764
Alt Symbol	TRABID
Species	Human
Gene Type	protein-coding
Description	zinc finger, RAN-binding domain containing 1
Other Description	TRAF-binding domain-containing protein|TRAF-binding protein domain|hTrabid|ubiquitin thioesterase ZRANB1|zinc finger Ran-binding domain-containing protein 1
Swissprots	Q5SQP6 Q69YK3 D3DRF4 B4DZ98 Q9UGI0
Accessions	EAW49252 EAW49253 Q9UGI0 AJ252060 CAB64449 AK302810 BAG64010 AK307386 AL832925 CAH10620 BC048281 BC152728 AAI52729 HG503330 XM_005269925 XP_005269982 XM_005269926 XP_005269983 XM_006717907 XP_006717970 XM_011539887 XP_011538189 NM_017580 NP_060050
Function	Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'- linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. {ECO:0000269|PubMed:18281465, ECO:0000269|PubMed:21834987, ECO:0000269|PubMed:22157957, ECO:0000269|PubMed:23827681}.
Subcellular Location	Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:11463333}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human ZRANB1 full length protein - ab188701 from Abcam Category Protein Prices $572.00 Sizes 50 µg Source Baculovirus infected Sf21 cells Species Human

ZRANB1 / TRABID Antibody Blocking Peptide - LS-E21708 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZRANB1 / TRABID Antibody Blocking Peptide - LS-E26787 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZRANB1 / TRABID Antibody Blocking Peptide - LS-E10341 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZRANB1-Antibody-C-term-Blocking-Peptide - BP9830b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TRABID/ZRANB1 blocking peptide - GTX88665-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Bovine

Recombinant Human His6-ZRANB1/Trabid, CF - E-560-050 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Contains a C-terminal 6-His tag

ZRANB1 Peptide - AC21-1619-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TRABID Peptide - 46-910P from ProSci Category Peptide Species Human

Recombinant Human ZRANB1, His-tagged - ZRANB1-158H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Ubiquitin thioesterase ZRANB1(ZRANB1) - CSB-YP883378HU CSB-EP883378HU CSB-BP883378HU CSB-MP883378HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human His6-ZRANB1/Trabid Protein, CF - E-560 from R&D Systems Category Protein Prices $269.00 Sizes 50 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Contains a C-terminal 6-His tag Species Human

His6-ZRANB1/Trabid - E-560 from Boston Biochem Prices $269.00 Sizes 50 µg

TRABID/ZRANB1, Peptide - MBS425231 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

ZRANB1/Trabid Recombinant Protein Antigen - NBP1-86918PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZRANB1/Trabid Recombinant Protein Antigen - NBP1-86917PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZRANB1/Trabid Recombinant Protein Antigen - NBP1-86916PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZRANB1 Peptide, Human - M34GP18376H from Creative Peptides Category Peptide Source Synthetic. Species Human

ZRANB1 fusion protein - Ag25798 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

ZRANB1 Immunizing peptide - orb16991 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

Recombinant Human His6-ZRANB1/Trabid Protein, CF - E-560 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Species Human

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