ZRANB1

Gene Symbol ZRANB1
Entrez Gene 54764
Alt Symbol TRABID
Species Human
Gene Type protein-coding
Description zinc finger, RAN-binding domain containing 1
Other Description TRAF-binding domain-containing protein|TRAF-binding protein domain|hTrabid|ubiquitin thioesterase ZRANB1|zinc finger Ran-binding domain-containing protein 1
Swissprots Q5SQP6 Q69YK3 D3DRF4 B4DZ98 Q9UGI0
Accessions EAW49252 EAW49253 Q9UGI0 AJ252060 CAB64449 AK302810 BAG64010 AK307386 AL832925 CAH10620 BC048281 BC152728 AAI52729 HG503330 XM_005269925 XP_005269982 XM_005269926 XP_005269983 XM_006717907 XP_006717970 XM_011539887 XP_011538189 NM_017580 NP_060050
Function Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'- linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. {ECO:0000269|PubMed:18281465, ECO:0000269|PubMed:21834987, ECO:0000269|PubMed:22157957, ECO:0000269|PubMed:23827681}.
Subcellular Location Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:11463333}.

TRABID CRISPR/Cas9 KO Plasmid (h) - sc-402852 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID HDR Plasmid (h) - sc-402852-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID Double Nickase Plasmid (h) - sc-402852-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID Double Nickase Plasmid (h2) - sc-402852-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID CRISPR Activation Plasmid (h) - sc-402852-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID CRISPR Activation Plasmid (h2) - sc-402852-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID Lentiviral Activation Particles (h) - sc-402852-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID Lentiviral Activation Particles (h2) - sc-402852-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRABID siRNA (h) - sc-90499 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRABID shRNA Plasmid (h) - sc-90499-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRABID shRNA (h) Lentiviral Particles - sc-90499-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZRANB1/Trabid RNAi - H00054764-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU151931 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23794 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23794 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11391 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11391

ZRANB1 siRNA (Human) - CRJ0205 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZRANB1 - MBS8223049 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZRANB1 (NM_017580.2) - SHH455808 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ZRANB1(NM_017580.2) - SHL162966 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZRANB1 siRNA - orb270706 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZRANB1 shRNA Plasmid (Human) - CHJ0205 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZRANB1 miRNA 3'UTR clone - MiUTR1H-11755 from Creative biogene

Species Reactivities Human
Search more