SRA1

Gene Symbol	SRA1
Entrez Gene	10011
Alt Symbol	SRA, SRAP, STRAA1, pp7684
Species	Human
Gene Type	protein-coding
Description	steroid receptor RNA activator 1
Other Description	steroid receptor RNA activator 1 (complexes with NCOA1)|steroid receptor RNA activator protein|steroid receptor coactivator
Swissprots	Q9HD15 Q9HD13 Q8IXM1 Q6NVU9 Q9HD14
Accessions	EAW62051 EAW62052 Q9HD15 AF092038 AF293024 AAG02114 AF293025 AAG02115 AF293026 AAG02116 AF318361 AAL55868 AI140060 AK024640 AK054960 BAG51445 BC040043 AAH40043 BC067895 BC152788 AAI52789 BC156760 AAI56761 BQ052761 BU553214 CX165918 DA311407 DQ286291 NM_001035235 NP_001030312 NM_001253764 NP_001240693 NR_045586 NR_045587
Function	Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. {ECO:0000269|PubMed:10199399, ECO:0000269|PubMed:12943696, ECO:0000269|PubMed:14517287, ECO:0000269|PubMed:15147866, ECO:0000269|PubMed:15351741}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12565891}. Cytoplasm {ECO:0000269|PubMed:12565891}.
Tissue Specificity	Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up- regulated in human tumors of the breast, ovary, and uterus. {ECO:0000269|PubMed:10199399, ECO:0000269|PubMed:12565891, ECO:0000269|PubMed:14517287}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SRA1 protein fragment - ab137163 from Abcam Category Protein Source E. coli Species Human

SRA1-Antibody-C-term-Blocking-Peptide - BP17404b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SRA1 / SRAP (90-236, His-tag) - AR50620PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

SRA1 / SRAP (90-236, His-tag) - AR50620PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

SRA1 / SRAP - P5876 from Acris Antibodies Category Protein Prices $500.00 Sizes 20 µg Species Human

SRA1, 90-236aa, Human, His tag, E.coli - 01-P1796 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

SRA1 fusion protein - ag20082 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SRA1 Human - PRPS-1281 from NeoScientific Category Protein Prices $65.00, $169.00, $1,560.00 Sizes 2 µg, 10 µg, 100 µg Source Escherichia Coli. Species Human

Recombinant Human steroid receptor RNA activator 1, His-tagged - SRA1-357H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Steroid receptor RNA activator 1(SRA1) - CSB-YP022648HU CSB-EP022648HU CSB-BP022648HU CSB-MP022648HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SRA1, 90-236aa, Human, His tag, E.coli - ATGP1796 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 4 µg, 20 µg, 100 µg Species Human

SRA Blocking Peptide - CBP4255 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

SRA Blocking Peptide - abx161466 from Abbexa Category Peptide Species Human, Mouse, Rat

Steroid Receptor RNA Activator 1 Protein (Recombinant) - abx263319 from Abbexa Category Protein

SRA1 / SRAP - TP320899 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SRA1 - PAT-81797-1 from Nordic BioSite Category Protein Species Human

SRA1 - PAT-81797-2 from Nordic BioSite Category Protein Species Human

Steroid Receptor RNA Activator 1, Human Recombinant - 228-21380-1 from RayBiotech Category Protein Species Human

SRA1, Recombinant Protein - MBS205353 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 20 µg, 100 µg Source E Coli Species Human

Steroid Receptor RNA Activator 1, Recombinant Protein - MBS146089 from MyBioSource Category Protein Prices $140.00, $205.00, $1,220.00 Sizes 2 µg, 10 µg, 100 µg Source E Coli

Steroid receptor RNA activator 1 (SRA1), Recombinant Protein - MBS1455897 from MyBioSource Category Protein Prices $990.00, $990.00, $1,215.00, $1,215.00, $1,500.00, $1,500.00, $1,965.00, $1,965.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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