SRA1

Gene Symbol SRA1
Entrez Gene 10011
Alt Symbol SRA, SRAP, STRAA1, pp7684
Species Human
Gene Type protein-coding
Description steroid receptor RNA activator 1
Other Description steroid receptor RNA activator 1 (complexes with NCOA1)|steroid receptor RNA activator protein|steroid receptor coactivator
Swissprots Q9HD15 Q9HD13 Q8IXM1 Q6NVU9 Q9HD14
Accessions EAW62051 EAW62052 Q9HD15 AF092038 AF293024 AAG02114 AF293025 AAG02115 AF293026 AAG02116 AF318361 AAL55868 AI140060 AK024640 AK054960 BAG51445 BC040043 AAH40043 BC067895 BC152788 AAI52789 BC156760 AAI56761 BQ052761 BU553214 CX165918 DA311407 DQ286291 NM_001035235 NP_001030312 NM_001253764 NP_001240693 NR_045586 NR_045587
Function Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand- dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. {ECO:0000269|PubMed:10199399, ECO:0000269|PubMed:12943696, ECO:0000269|PubMed:14517287, ECO:0000269|PubMed:15147866, ECO:0000269|PubMed:15351741}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12565891}. Cytoplasm {ECO:0000269|PubMed:12565891}.
Tissue Specificity Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up- regulated in human tumors of the breast, ovary, and uterus. {ECO:0000269|PubMed:10199399, ECO:0000269|PubMed:12565891, ECO:0000269|PubMed:14517287}.

SRA CRISPR/Cas9 KO Plasmid (h) - sc-404308 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA HDR Plasmid (h) - sc-404308-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA Double Nickase Plasmid (h) - sc-404308-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA Double Nickase Plasmid (h2) - sc-404308-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA CRISPR Activation Plasmid (h) - sc-404308-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA CRISPR Activation Plasmid (h2) - sc-404308-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA Lentiviral Activation Particles (h) - sc-404308-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA Lentiviral Activation Particles (h2) - sc-404308-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRA siRNA (h) - sc-38461 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SRA shRNA Plasmid (h) - sc-38461-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SRA shRNA (h) Lentiviral Particles - sc-38461-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU229221 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20554 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20554 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05325 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05325

SRA1 siRNA (Human) - CRH6739 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRA1 - MBS829601 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SRA1 (NM_001035235.3) - SHH417624 from Creative biogene

Category siRNA
Species Reactivities Human

SRA1 shRNA Plasmid (Human) - CHH6739 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SRA1 miRNA 3'UTR clone - MiUTR3H-06294 from Creative biogene

Species Reactivities Human
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