SMC3

Gene Symbol	SMC3
Entrez Gene	9126
Alt Symbol	BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Species	Human
Gene Type	protein-coding
Description	structural maintenance of chromosomes 3
Other Description	SMC protein 3|basement membrane-associated chondroitin proteoglycan|chondroitin sulfate proteoglycan 6 (bamacan)|chromosome-associated polypeptide|structural maintenance of chromosomes protein 3
Swissprots	Q5T482 O60464 A8K156 Q9UQE7
Accessions	EAW49557 EAW49558 Q9UQE7 AF020043 AAC14893 AF067163 AAD32447 AJ005015 CAA06289 AK289771 BAF82460 AK315845 BAF98736 BC047324 AAH47324 CA439554 NM_005445 NP_005436
Function	Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement. {ECO:0000269|PubMed:11076961, ECO:0000269|PubMed:19907496}.
Subcellular Location	Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation. The phosphorylated form at Ser- 1083 is preferentially associated with unsynapsed chromosomal regions (By similarity). {ECO:0000250}.
Top Pathways	Cell cycle, Oocyte meiosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-SMC3 Antibody, Affinity Purified - PLA0019 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Bcl-2-like protein 11 (BCL2L11), Human, ELISA Kit - CSB-EL002615HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Dermcidin (DCD), Human, ELISA Kit - SEC896Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.061ng/mL Range 0.156-10ng/mL

structural maintenance of chromosomes 3, ELISA Kit - MBS9329719 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0 pg/ml. Range 31.2 pg/ml - 1000 pg/ml.

ELISA Kit for Dermcidin (DCD) - SEC896Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.32ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human Bcl2L11(Bcl-2 Like Protein 11) ELISA Kit - E-EL-H0582 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mLng/mL Range 0.31~20 ng/mL

Human SMC3 ELISA Kit - E098116 from Biobool Category ELISA Kit

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9354592 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9349474 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9364958 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9365545 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9369360 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9350526 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9370087 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9353782 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9349893 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9368989 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9350884 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9356000 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9361102 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9361021 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9347057 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9349070 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9380244 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Structural Maintenance of Chromosomes Protein 3 (SMC3), ELISA Kit - MBS9358086 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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