WDR83

Gene Symbol WDR83
Entrez Gene 84292
Alt Symbol MORG1
Species Human
Gene Type protein-coding
Description WD repeat domain 83
Other Description MAPK organizer 1|WD repeat domain-containing protein 83|mitogen-activated protein kinase organizer 1
Swissprots Q53FT6 B2RAF1 Q9BRX9
Accessions EAW84282 EAW84283 EAW84284 Q9BRX9 AK074525 AK223195 BAD96915 AK314164 BAG36848 BC005870 AAH05870 CB143206 HQ447831 ADQ32315 Z46189 XM_011528358 XP_011526660 NM_001099737 NP_001093207 NM_032332 NP_115708 NR_029375
Function Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing. {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly cytoplasmic. Partially nuclear. {ECO:0000250}.

MORG1 CRISPR/Cas9 KO Plasmid (h) - sc-408296 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 HDR Plasmid (h) - sc-408296-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 Double Nickase Plasmid (h) - sc-408296-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 Double Nickase Plasmid (h2) - sc-408296-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 CRISPR Activation Plasmid (h) - sc-408296-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 CRISPR Activation Plasmid (h2) - sc-408296-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 Lentiviral Activation Particles (h) - sc-408296-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 Lentiviral Activation Particles (h2) - sc-408296-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MORG1 siRNA (h) - sc-75812 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MORG1 shRNA Plasmid (h) - sc-75812-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MORG1 shRNA (h) Lentiviral Particles - sc-75812-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU012411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22862 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22862 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00116 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00116

WDR83 siRNA (Human) - CRJ3416 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Morg1 RNAi - H00084292-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

WDR83 - MBS8218197 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human WDR83 (NM_032332.3) - SHH446580 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MORG1(NM_032332.3) - SHH195995 from Creative biogene

Category siRNA
Species Reactivities Human

Human WDR83 siRNA - orb273917 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

WDR83 shRNA Plasmid (Human) - CHJ3416 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

WDR83 miRNA 3'UTR clone - MiUTR1H-06384 from Creative biogene

Species Reactivities Human
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