GUCA1A

Gene Symbol	GUCA1A
Entrez Gene	2978
Alt Symbol	C6orf131, COD3, CORD14, GCAP, GCAP1, GUCA, GUCA1, dJ139D8.6
Species	Human
Gene Type	protein-coding
Description	guanylate cyclase activator 1A (retina)
Other Description	GCAP 1|cone dystrophy 3|guanylate cyclase-activating protein, photoreceptor 1|guanylin 1, retina|guanylyl cyclase-activating protein 1
Swissprots	Q9NU14 B3KWT4 Q7Z6T1 P43080
Accessions	AAA60542 AFK80059 AFK80060 EAX04084 P43080 AK125780 BAG54246 AK313865 BAG36593 BC031663 AAH31663 DB049592 DQ891302 ABM82228 DQ894487 ABM85413 L36859 AAA60541 XM_006715073 XP_006715136 XM_011514536 XP_011512838 XM_011514537 XP_011512839 XM_011514538 XP_011512840 XM_011514539 XP_011512841 NM_000409 NP_000400
Function	Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Subcellular Location	Membrane; Lipid-anchor.
Tissue Specificity	Retina; cone outer and inner segments, in particular, in disk membrane regions, and to a lesser extent rod inner and outer segments.
Top Pathways	Olfactory transduction, Phototransduction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GCAP1 full length protein - ab117014 from Abcam Category Protein Source Wheat germ Species Human

Human GCAP1 protein fragment - ab158609 from Abcam Category Protein Source Wheat germ Species Human

GCAP / GUCA1A Antibody Blocking Peptide - LS-E3819 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GCAP / GUCA1A Antibody Blocking Peptide - LS-E19538 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GCAP1 Protein - H00002978-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GCAP1 Protein - H00002978-P01 from Novus Biologicals Category Protein Prices $305.00, $445.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GCAP1 Peptide - P0575 from Novus Biologicals Category Peptide Species Human

GCAP1-Antibody-C-term-Blocking-Peptide - BP1567b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCAP1 Protein - GTX109137-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Human GUCA1A protein (GST Tag) - orb138956 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Human GUCA1A protein - orb138957 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

GUCA1A Blocking Peptide - 33R-5562 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GCAP1 / GUCA1A - H00002978-P01-02 from Acris Antibodies Category Protein Prices $300.00 Sizes 2 µg Source in vitro transl. Species Human

GCAP1 / GUCA1A - H00002978-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

GCAP1 / GUCA1A - H00002978-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GUCA1A fusion protein - ag14410 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GUCA1A fusion protein - Ag4017 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human GUCA1A, Gly & Pro tagged - GUCA1A-407H from Creative Biomart Category Protein Source Baculovirus-Insect cells Species Human

Recombinant Human GUCA1A, His-GST tagged - GUCA1A-487H from Creative Biomart Category Protein Source Baculovirus-Insect cells Species Human

Recombinant Human GUCA1A - GUCA1A-28157TH from Creative Biomart Category Protein Source Wheat germ

Human GCAP1 / GUCA1A Protein (His & GST Tag) - 14565-H20B-20 from Sino Biological Category Protein Prices $138.00, $138.00 Sizes 20 µg, 100 µg Source Baculovirus-Insect Cells Species Human

Human GCAP1 / GUCA1A Protein - 14565-HNCB-100 from Sino Biological Category Protein Prices $348.00, $348.00 Sizes 20 µg, 100 µg Source Baculovirus-Insect Cells Species Human

Recombinant Human Guanylyl cyclase-activating protein 1(GUCA1A) - CSB-YP010044HU CSB-EP010044HU CSB-BP010044HU CSB-MP010044HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GUCA1A Protein - abx163434 from Abbexa Category Protein Species Human, Mouse, Rat

GCAP1 / GUCA1A - TP306595 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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