GUCA1A

Gene Symbol GUCA1A
Entrez Gene 2978
Alt Symbol C6orf131, COD3, CORD14, GCAP, GCAP1, GUCA, GUCA1, dJ139D8.6
Species Human
Gene Type protein-coding
Description guanylate cyclase activator 1A (retina)
Other Description GCAP 1|cone dystrophy 3|guanylate cyclase-activating protein, photoreceptor 1|guanylin 1, retina|guanylyl cyclase-activating protein 1
Swissprots Q9NU14 B3KWT4 Q7Z6T1 P43080
Accessions AAA60542 AFK80059 AFK80060 EAX04084 P43080 AK125780 BAG54246 AK313865 BAG36593 BC031663 AAH31663 DB049592 DQ891302 ABM82228 DQ894487 ABM85413 L36859 AAA60541 XM_006715073 XP_006715136 XM_011514536 XP_011512838 XM_011514537 XP_011512839 XM_011514538 XP_011512840 XM_011514539 XP_011512841 NM_000409 NP_000400
Function Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Subcellular Location Membrane; Lipid-anchor.
Tissue Specificity Retina; cone outer and inner segments, in particular, in disk membrane regions, and to a lesser extent rod inner and outer segments.
Top Pathways Olfactory transduction, Phototransduction

GCAP1 (7) - sc-136313 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GCAP1 (7): sc-136313. Western blot analysis of GCAP1 expression in MDCK whole cell lysate.

GCAP1 (C-1) - sc-390679 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GCAP1 (C-1): sc-390679. Western blot analysis of GCAP1 expression in non-transfected: sc-117752 (A) and human GCAP1 transfected: sc-171956 (B) 293T whole cell lysates.

GCAP1 (E-5) - sc-390695 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GCAP1 (E-5): sc-390695. Western blot analysis of GCAP1 expression in non-transfected: sc-117752 (A) and human GCAP1 transfected: sc-171956 (B) 293T whole cell lysates.

GCAP1 (F-6) - sc-390678 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GCAP1 (F-6): sc-390678. Western blot analysis of GCAP1 expression in non-transfected: sc-117752 (A) and human GCAP1 transfected: sc-171956 (B) 293T whole cell lysates.

GCAP1 (G2G4) - sc-59542 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GCAP1 (G2G4): sc-59542. Western blot analysis of GCAP1 expression in non-transfected: sc-117752 (A) and human GCAP1 transfected: sc-114427 (B) 293T whole cell lysate.

GCAP1 (FL-201) - sc-366052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GCAP1 (FL-201): sc-366052. Western blot analysis of GCAP1 expression in non-transfected: sc-117752 (A) and human GCAP1 transfected: sc-114427 (B) 293T whole cell lysates.

GCAP1 (N-20) - sc-21050 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GCAP1 (N-20): sc-21050. Western blot analysis of GCAP1 expression in mouse lung tissue extract.

Anti-GCAP1 antibody - Carboxyterminal end - ab38593 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GCAP1 antibody - Carboxyterminal end (ab38593) at 1/100 dilution + Y79 cell lysate

Anti-GCAP / GUCA1A Antibody - LS-C123674 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-GCAP / GUCA1A Antibody (C-Terminus, APC) - LS-C244584 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCAP / GUCA1A Antibody (C-Terminus, AP) - LS-C244583 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCAP / GUCA1A Antibody (C-Terminus, Biotin) - LS-C244585 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCAP / GUCA1A Antibody (C-Terminus, FITC) - LS-C244586 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCAP / GUCA1A Antibody (C-Terminus, PE) - LS-C244587 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCAP / GUCA1A Antibody (C-Terminus, Azide-free, HRP) - LS-C247618 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCAP / GUCA1A Antibody (C-Terminus) - LS-C330461 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCAP / GUCA1A Antibody (aa36-85) - LS-C111552 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GUCA1A / GCAP1 antibody LS-C111552 Western blot of Fetal Kidney lysate.

Anti-GCAP / GUCA1A Antibody (aa160-191) - LS-C97757 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-GCAP / GUCA1A Antibody (clone 2F7) - LS-C197382 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F7
Western Blot analysis of GUCA1A expression in transfected 293T cell line by GUCA1A monoclonal antibody (M04), clone 2F7.Lane 1: GUCA1A transfected lysate(22.9 KDa).Lane 2: Non-transfected lysate.

GCAP1 Antibody - NBP1-54868 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GCAP1 Antibody [NBP1-54868] - Human kidney lysate, concentration 0.2-1 ug/ml.

GCAP1 Antibody (2F7) - H00002978-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F7

GCAP1 Antibody - H00002978-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

GCAP1 Polyclonal Antibody - bs-13306R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GCAP1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13306R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GCAP1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13306R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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