GUCA1A

Gene Symbol	GUCA1A
Entrez Gene	2978
Alt Symbol	C6orf131, COD3, CORD14, GCAP, GCAP1, GUCA, GUCA1, dJ139D8.6
Species	Human
Gene Type	protein-coding
Description	guanylate cyclase activator 1A (retina)
Other Description	GCAP 1|cone dystrophy 3|guanylate cyclase-activating protein, photoreceptor 1|guanylin 1, retina|guanylyl cyclase-activating protein 1
Swissprots	Q9NU14 B3KWT4 Q7Z6T1 P43080
Accessions	AAA60542 AFK80059 AFK80060 EAX04084 P43080 AK125780 BAG54246 AK313865 BAG36593 BC031663 AAH31663 DB049592 DQ891302 ABM82228 DQ894487 ABM85413 L36859 AAA60541 XM_006715073 XP_006715136 XM_011514536 XP_011512838 XM_011514537 XP_011512839 XM_011514538 XP_011512840 XM_011514539 XP_011512841 NM_000409 NP_000400
Function	Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Subcellular Location	Membrane; Lipid-anchor.
Tissue Specificity	Retina; cone outer and inner segments, in particular, in disk membrane regions, and to a lesser extent rod inner and outer segments.
Top Pathways	Olfactory transduction, Phototransduction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GCAP1 CRISPR/Cas9 KO Plasmid (h) - sc-410808 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 HDR Plasmid (h) - sc-410808-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 Double Nickase Plasmid (h) - sc-410808-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 Double Nickase Plasmid (h2) - sc-410808-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 CRISPR Activation Plasmid (h) - sc-410808-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 CRISPR Activation Plasmid (h2) - sc-410808-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 Lentiviral Activation Particles (h) - sc-410808-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 Lentiviral Activation Particles (h2) - sc-410808-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCAP1 siRNA (h) - sc-40628 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCAP1 shRNA Plasmid (h) - sc-40628-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCAP1 shRNA (h) Lentiviral Particles - sc-40628-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCAP1 RNAi - H00002978-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

GCAP1 RNAi - H00002978-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU118261 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9793 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9793 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06126 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr06126

GUCA1A siRNA (Human) - CRH2017 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GUCA1A - MBS8234156 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human GUCA1A (NM_000409.3) - SHH309270 from Creative biogene Category siRNA Species Reactivities Human

Human GUCA1A siRNA - orb262519 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GUCA1A shRNA Plasmid (Human) - CHH2017 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

GUCA1A miRNA 3'UTR clone - MiUTR3H-03301 from Creative biogene Species Reactivities Human

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