Gene Symbol | LIPE |
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Entrez Gene | 3991 |
Alt Symbol | AOMS4, FPLD6, HSL, LHS |
Species | Human |
Gene Type | protein-coding |
Description | lipase, hormone-sensitive |
Other Description | hormone-sensitive lipase|hormone-sensitive lipase testicular isoform |
Swissprots | Q6NSL7 Q3LRT2 Q05469 |
Accessions | AAA69810 ABA03168 EAW57135 Q05469 AK292482 BAF85171 AK309893 BC029301 BC029961 BC070041 AAH70041 U40002 AAC50666 XM_005258937 XP_005258994 XM_005258938 XP_005258995 XM_005258939 XP_005258996 XM_005258940 XP_005258997 XM_005258941 XP_005258998 XM_006723218 XP_006723281 NM_005357 NP_005348 |
Function | In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. |
Subcellular Location | Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation. |
Top Pathways | Insulin signaling pathway, AMPK signaling pathway, cAMP signaling pathway |
Human Hormone sensitive lipase peptide - ab51487 from Abcam
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Human Hormone sensitive lipase peptide - ab74632 from Abcam
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LIPE / HSL Antibody Blocking Peptide - LS-E30282 from LifeSpan Bioscience
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LIPE / HSL Antibody Blocking Peptide - LS-E10093 from LifeSpan Bioscience
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Hormone-sensitive Lipase/HSL Peptide - NBP1-76735PEP from Novus Biologicals
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LIPE-Antibody-C-term-Blocking-Peptide - BP9376b from Abgent, a WuXi AppTec company
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HSL (phospho-Ser855) Blocking Peptide - abx062151 from Abbexa
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HSL Blocking Peptide - abx062883 from Abbexa
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LIPE Control Peptide - AP30510CP-N from Acris Antibodies
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Lipe Peptide - 3965P from ProSci
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LIPE fusion protein - ag11360 from Proteintech Group
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Recombinant Human LIPE, His-tagged - LIPE-26698TH from Creative Biomart
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Recombinant Human LIPE, His-tagged - LIPE-8392H from Creative Biomart
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Recombinant Human LIPE, MYC/DDK-tagged - LIPE-8393H from Creative Biomart
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Recombinant Lipase, Hormone Sensitive (LIPE) - RPB276Hu01 from Uscn Life Science Inc.
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Recombinant Lipase, Hormone Sensitive (LIPE) - RPB276Ra01 from Uscn Life Science Inc.
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HSL Blocking Peptide - CBP1689 from Cohesion Biosciences
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HSL (pS855) Blocking Peptide - CBP3257 from Cohesion Biosciences
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HSL (pS552) Blocking Peptide - CBP4059 from Cohesion Biosciences
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HSL (P548) Peptide - AP0372P from Bioworld Technology
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HSL (A546) Peptide - BS2742P from Bioworld Technology
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p-HSL (S855) Peptide - BS4234P from Bioworld Technology
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Recombinant Lipase, Hormone Sensitive (LIPE) - RPB276Hu01 from Cloud-clone
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Recombinant Human Hormone-sensitive lipase(LIPE) ,partial - CSB-YP012975HU CSB-EP012975HU CSB-BP012975HU CSB-MP012975HU from Cusabio
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LIPE - TP309729 from Acris Antibodies
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