LIPE

Gene Symbol LIPE
Entrez Gene 3991
Alt Symbol AOMS4, FPLD6, HSL, LHS
Species Human
Gene Type protein-coding
Description lipase, hormone-sensitive
Other Description hormone-sensitive lipase|hormone-sensitive lipase testicular isoform
Swissprots Q6NSL7 Q3LRT2 Q05469
Accessions AAA69810 ABA03168 EAW57135 Q05469 AK292482 BAF85171 AK309893 BC029301 BC029961 BC070041 AAH70041 U40002 AAC50666 XM_005258937 XP_005258994 XM_005258938 XP_005258995 XM_005258939 XP_005258996 XM_005258940 XP_005258997 XM_005258941 XP_005258998 XM_006723218 XP_006723281 NM_005357 NP_005348
Function In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
Subcellular Location Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation.
Top Pathways Insulin signaling pathway, AMPK signaling pathway, cAMP signaling pathway

HSL CRISPR/Cas9 KO Plasmid (h) - sc-401341 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL HDR Plasmid (h) - sc-401341-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL Double Nickase Plasmid (h) - sc-401341-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL Double Nickase Plasmid (h2) - sc-401341-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL CRISPR Activation Plasmid (h) - sc-401341-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL CRISPR Activation Plasmid (h2) - sc-401341-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL Lentiviral Activation Particles (h) - sc-401341-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL Lentiviral Activation Particles (h2) - sc-401341-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL siRNA (h) - sc-106861 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HSL shRNA Plasmid (h) - sc-106861-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HSL shRNA (h) Lentiviral Particles - sc-106861-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU004801 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11744 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11744 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03258 from Sigma-Aldrich

Category miRNA

LIPE siRNA (Human) - CRH2702 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HSL CRISPR/Cas9 KO Plasmid (h2) - sc-401341-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSL HDR Plasmid (h2) - sc-401341-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human LIPE (NM_005357.2) - SHH330655 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LIPE(NM_005357.2) - SHH150923 from Creative biogene

Category siRNA
Species Reactivities Human

LIPE shRNA Plasmid (Human) - CHH2702 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LIPE miRNA 3'UTR clone - MiUTR1H-05697 from Creative biogene

Species Reactivities Human
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