MPL

Gene Symbol	MPL
Entrez Gene	4352
Alt Symbol	C-MPL, CD110, MPLV, THCYT2, TPOR
Species	Human
Gene Type	protein-coding
Description	MPL proto-oncogene, thrombopoietin receptor
Other Description	TPO-R|myeloproliferative leukemia protein|myeloproliferative leukemia virus oncogene|proto-oncogene c-Mpl|thrombopoietin receptor
Swissprots	Q5JUZ0 P40238
Accessions	AAB08424 AAB08425 EAX07103 EAX07104 EAX07105 P40238 BC140298 AAI40299 BC153092 AAI53093 DQ234353 ABB29982 KF964490 AHL44293 M90102 AAA69971 M90103 AAA69972 XM_011541478 XP_011539780 NM_005373 NP_005364
Function	Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TPOR full length protein - ab152537 from Abcam Category Protein Source Wheat germ Species Human

Thrombopoietin R/Tpo R Recombinant Protein - H00004352-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Thrombopoietin R/Tpo R Protein - H00004352-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

Recombinant Human Thrombopoietin R, CF - 4444-TR-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Ser25-Trp491, with a C-terminal 6-His tag

Human CD110 protein - orb83471 from Biorbyt Category Protein Prices $162.00, $400.00, $1,063.00 Sizes 5 μg, 20 μg, 100 μg Source CHO Species Human

Cynomolgus CD110 protein - orb83856 from Biorbyt Category Protein Prices $162.00, $400.00, $1,063.00 Sizes 5 μg, 20 μg, 100 μg Source Cynomolgus Species Human

Human MPL protein - orb244381 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CD110 protein - orb83140 from Biorbyt Category Protein Prices $162.00, $400.00, $1,063.00 Sizes 5 μg, 20 μg, 100 μg Source Human Species Human

Human MPL protein - orb245925 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human MPL Protein - abx068134 from Abbexa Category Protein Source E.coli Species Human

CD110 - H00004352-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD110 - H00004352-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD110 - H00004352-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MPL fusion protein - ag18933 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MPL fusion protein - ag19035 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Myeloproliferative Leukemia Virus Oncogene (MPL) - RPB468Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Myeloproliferative Leukemia Virus Oncogene (MPL) - RPB468Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Myeloproliferative Leukemia Virus Oncogene (MPL) - RPB468Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Thrombopoietin receptor(MPL) - CSB-YP014755HU CSB-BP014755HU CSB-MP014755HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Thrombopoietin receptor(MPL) - CSB-EP014755HU from Cusabio Category Protein Source Yeast Species Human

Recombinant Human Thrombopoietin R Protein, CF - 4444-TR from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Ser25-Trp491, with a C-terminal 6-His tag Species Human

Myeloproliferative Leukemia Virus Oncogene (MPL) - RPU142860 from Biomatik Category Protein Prices $262.90, $525.80, $788.70 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Thrombopoietin receptor(MPL) , Recombinant Protein - MBS960212 from MyBioSource Category Protein Prices $2,035.00, $2,035.00, $2,500.00, $2,500.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MPL Peptide, Human - M34GP09675H from Creative Peptides Category Peptide Source Synthetic. Species Human

MPL Recombinant Protein (OPCA01731) - OPCA01731 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

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