MPL

Gene Symbol MPL
Entrez Gene 4352
Alt Symbol C-MPL, CD110, MPLV, THCYT2, TPOR
Species Human
Gene Type protein-coding
Description MPL proto-oncogene, thrombopoietin receptor
Other Description TPO-R|myeloproliferative leukemia protein|myeloproliferative leukemia virus oncogene|proto-oncogene c-Mpl|thrombopoietin receptor
Swissprots Q5JUZ0 P40238
Accessions AAB08424 AAB08425 EAX07103 EAX07104 EAX07105 P40238 BC140298 AAI40299 BC153092 AAI53093 DQ234353 ABB29982 KF964490 AHL44293 M90102 AAA69971 M90103 AAA69972 XM_011541478 XP_011539780 NM_005373 NP_005364
Function Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

c-Mpl CRISPR/Cas9 KO Plasmid (h) - sc-403035 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl HDR Plasmid (h) - sc-403035-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl Double Nickase Plasmid (h) - sc-403035-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl Double Nickase Plasmid (h2) - sc-403035-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl CRISPR Activation Plasmid (h) - sc-403035-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl CRISPR Activation Plasmid (h2) - sc-403035-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl Lentiviral Activation Particles (h) - sc-403035-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl Lentiviral Activation Particles (h2) - sc-403035-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Mpl siRNA (h) - sc-29853 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Mpl shRNA Plasmid (h) - sc-29853-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Mpl shRNA (h) Lentiviral Particles - sc-29853-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN14500 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14500 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MPL siRNA (Human) - CRH2955 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Thrombopoietin R/Tpo R RNAi - H00004352-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MPL (NM_005373.2) - SHH343884 from Creative biogene

Category siRNA
Species Reactivities Human

MPL shRNA Plasmid (Human) - CHH2955 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MPL miRNA 3'UTR clone - MiUTR4H-TG05600 from Creative biogene

Species Reactivities Human
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