FGD2

Gene Symbol FGD2
Entrez Gene 221472
Alt Symbol ZFYVE4
Species Human
Gene Type protein-coding
Description FYVE, RhoGEF and PH domain containing 2
Other Description FGD1 family, member 2|FLJ00276 protein|FYVE, RhoGEF and PH domain-containing protein 2|zinc finger FYVE domain-containing protein 4
Swissprots Q9H7M2 Q7Z6J4 Q8N868 Q5T8I1 Q8IZ32 Q6ZNL5 Q6P6A8
Accessions EAX03932 EAX03933 Q7Z6J4 AK024456 BAB15746 AK092732 AK097230 BAC04982 AK097981 AK098248 AK131079 BAC85129 AK290419 BAF83108 AK300964 BAG62589 AK301156 BAG62746 BC023645 AAH23645 BC053655 AAH53655 BC062363 BX648164 DQ893612 ABM84538 DQ894928 ABM85854 XM_005248911 XP_005248968 XM_005248912 XP_005248969 XM_005248913 XP_005248970 XM_005248914 XP_005248971 XM_006715016 XP_006715079 XM_011514371 XP_011512673 XM_011514372 XP_011512674 XM_011514373 XP_011512675 XM_011514374 XP_011512676 XR_926106 NM_173558 NP_775829
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5- bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4- monophosphate and phosphatidylinositol 3-monophosphate (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000305}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Early endosome {ECO:0000250}. Early endosome membrane {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}. Note=Recruitment to the endosome and ruffle membrane requires the presence of phosphoinositides. {ECO:0000250}.

Human FGD2 full length protein - ab165971 from Abcam

Category Protein
Source Wheat germ
Species Human
ab165971 on a 12.5% SDS-PAGE stained with Coomassie Blue.

FGD2-Antibody-C-term-Blocking-Peptide - BP13191b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

FGD2 - H00221472-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

FGD2 - H00221472-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

FGD2 fusion protein - ag2856 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human FYVE, RhoGEF and PH domain-containing protein 2(FGD2) - CSB-YP768777HU CSB-EP768777HU CSB-BP768777HU CSB-MP768777HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

FGD2 - TP305644 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
FGD2

FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), Recombinant Protein - MBS1424412 from MyBioSource

Category Protein
Prices $1,455.00, $1,455.00, $1,685.00, $1,685.00, $2,470.00, $2,470.00, $2,915.00, $2,915.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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