FGD2

Gene Symbol FGD2
Entrez Gene 221472
Alt Symbol ZFYVE4
Species Human
Gene Type protein-coding
Description FYVE, RhoGEF and PH domain containing 2
Other Description FGD1 family, member 2|FLJ00276 protein|FYVE, RhoGEF and PH domain-containing protein 2|zinc finger FYVE domain-containing protein 4
Swissprots Q9H7M2 Q7Z6J4 Q8N868 Q5T8I1 Q8IZ32 Q6ZNL5 Q6P6A8
Accessions EAX03932 EAX03933 Q7Z6J4 AK024456 BAB15746 AK092732 AK097230 BAC04982 AK097981 AK098248 AK131079 BAC85129 AK290419 BAF83108 AK300964 BAG62589 AK301156 BAG62746 BC023645 AAH23645 BC053655 AAH53655 BC062363 BX648164 DQ893612 ABM84538 DQ894928 ABM85854 XM_005248911 XP_005248968 XM_005248912 XP_005248969 XM_005248913 XP_005248970 XM_005248914 XP_005248971 XM_006715016 XP_006715079 XM_011514371 XP_011512673 XM_011514372 XP_011512674 XM_011514373 XP_011512675 XM_011514374 XP_011512676 XR_926106 NM_173558 NP_775829
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5- bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4- monophosphate and phosphatidylinositol 3-monophosphate (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000305}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Early endosome {ECO:0000250}. Early endosome membrane {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}. Note=Recruitment to the endosome and ruffle membrane requires the presence of phosphoinositides. {ECO:0000250}.

FGD2 CRISPR/Cas9 KO Plasmid (h) - sc-410385 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 HDR Plasmid (h) - sc-410385-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 Double Nickase Plasmid (h) - sc-410385-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 Double Nickase Plasmid (h2) - sc-410385-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 CRISPR Activation Plasmid (h) - sc-410385-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 CRISPR Activation Plasmid (h2) - sc-410385-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 Lentiviral Activation Particles (h) - sc-410385-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 Lentiviral Activation Particles (h2) - sc-410385-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FGD2 siRNA (h) - sc-41713 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGD2 shRNA Plasmid (h) - sc-41713-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGD2 shRNA (h) Lentiviral Particles - sc-41713-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU154311 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8640 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8640 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07056 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07056

FGD2 siRNA (Human) - CRJ6519 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FGD2 - MBS8216605 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FGD2 (NM_173558.3) - SHH294301 from Creative biogene

Category siRNA
Species Reactivities Human

Human FGD2 siRNA - orb277020 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FGD2 shRNA Plasmid (Human) - CHJ6519 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FGD2 miRNA 3'UTR clone - MiUTR3H-07367 from Creative biogene

Species Reactivities Human
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