FGD2
| Gene Symbol | FGD2 |
|---|---|
| Entrez Gene | 221472 |
| Alt Symbol | ZFYVE4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | FYVE, RhoGEF and PH domain containing 2 |
| Other Description | FGD1 family, member 2|FLJ00276 protein|FYVE, RhoGEF and PH domain-containing protein 2|zinc finger FYVE domain-containing protein 4 |
| Swissprots | Q9H7M2 Q7Z6J4 Q8N868 Q5T8I1 Q8IZ32 Q6ZNL5 Q6P6A8 |
| Accessions | EAX03932 EAX03933 Q7Z6J4 AK024456 BAB15746 AK092732 AK097230 BAC04982 AK097981 AK098248 AK131079 BAC85129 AK290419 BAF83108 AK300964 BAG62589 AK301156 BAG62746 BC023645 AAH23645 BC053655 AAH53655 BC062363 BX648164 DQ893612 ABM84538 DQ894928 ABM85854 XM_005248911 XP_005248968 XM_005248912 XP_005248969 XM_005248913 XP_005248970 XM_005248914 XP_005248971 XM_006715016 XP_006715079 XM_011514371 XP_011512673 XM_011514372 XP_011512674 XM_011514373 XP_011512675 XM_011514374 XP_011512676 XR_926106 NM_173558 NP_775829 |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5- bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4- monophosphate and phosphatidylinositol 3-monophosphate (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000305}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Early endosome {ECO:0000250}. Early endosome membrane {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}. Note=Recruitment to the endosome and ruffle membrane requires the presence of phosphoinositides. {ECO:0000250}. |
FGD2 (G-16) - sc-11113 from Santa Cruz Biotechnology
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FGD2 (V-15) - sc-11114 from Santa Cruz Biotechnology
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Anti-FGD2 antibody - ab122040 from Abcam
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Anti-FGD2 antibody [EPR15306] - N-terminal - ab185968 from Abcam
![All lanes : Anti-FGD2 antibody [EPR15306] - N-terminal (ab185968) at 1/10000 dilutionLane 1 : Human tonsil lysateLane 2 : Human lymph node lysateLane 3 : Raji lysateLysates/proteins at 20 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_2/18566_ab185968-218870-ab185968WB.jpg)
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Anti-FGD2 Antibody (aa508-537) - LS-C166125 from LifeSpan Bioscience
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Anti-FGD2 Antibody (aa508-537, AP) - LS-C257205 from LifeSpan Bioscience
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Anti-FGD2 Antibody (aa508-537, APC) - LS-C257206 from LifeSpan Bioscience
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Anti-FGD2 Antibody (aa508-537, Biotin) - LS-C257207 from LifeSpan Bioscience
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Anti-FGD2 Antibody (aa508-537, FITC) - LS-C257208 from LifeSpan Bioscience
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Anti-FGD2 Antibody (aa508-537, Azide-free, HRP) - LS-C257209 from LifeSpan Bioscience
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Anti-FGD2 Antibody (aa508-537, PE) - LS-C257210 from LifeSpan Bioscience
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Anti-FGD2 Antibody (aa507-537) - LS-C321360 from LifeSpan Bioscience
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ANTI-FGD2 (C-TERM) antibody produced in rabbit - SAB1303269 from Sigma-Aldrich
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Anti-FGD2 antibody produced in rabbit - HPA029145 from Sigma-Aldrich
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FGD2-Antibody-C-term - AP13191b from Abgent, a WuXi AppTec company
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FGD2 Antibody - C-terminal region (OAAB09495) - OAAB09495 from Aviva Systems Biology
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FGD2 antibody - 12187-1-AP from Proteintech Group
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FYVE, RhoGEF and PH domain containing 2 , Polyclonal Antibody - MBS710785 from MyBioSource
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FGD2 Antibody - EPP13055 from Elabscience
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Anti-FGD2 (aa 16-110) polyclonal antibody - DPABH-20359 from Creative Diagnostics
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Anti-FGD2 monoclonal antibody - DCABH-200568 from Creative Diagnostics
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FGD2, Polyclonal Antibody - MBS9201657 from MyBioSource
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FGD2 Antibody - 56-911 from ProSci
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FGD2 antibody - 27068-1-AP from Proteintech Group
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