Gene Symbol | MRPL41 |
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Entrez Gene | 64975 |
Alt Symbol | BMRP, MRP-L27, MRPL27, PIG3, RPML27 |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial ribosomal protein L41 |
Other Description | 39S ribosomal protein L27 homolog|39S ribosomal protein L41, mitochondrial|L41mt|MRP-L27 homolog|MRP-L41|bcl-2-interacting mitochondrial ribosomal protein L41|cell proliferation-inducing gene 3 protein|proliferation-inducing gene 3 |
Swissprots | Q96Q49 Q8IXM3 |
Accessions | BAB54952 EAW88399 Q8IXM3 AI091177 AY232291 AAP69986 BC040035 AAH40035 BM919526 NM_032477 NP_115866 |
Function | Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. {ECO:0000269|PubMed:16024796, ECO:0000269|PubMed:16256947}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:16024796}. |
Tissue Specificity | Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level). {ECO:0000269|PubMed:15547950}. |
MRP-L41 (H-10) - sc-514312 from Santa Cruz Biotechnology
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MRP-L41 (C-13) - sc-107252 from Santa Cruz Biotechnology
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MRP-L41 (N-14) - sc-107253 from Santa Cruz Biotechnology
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MRP-L41 (P-16) - sc-107254 from Santa Cruz Biotechnology
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Anti-MRPL41 antibody - ab121821 from Abcam
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Anti-MRPL41 antibody - ab121922 from Abcam
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Anti-MRPL41 antibody - C-terminal - ab135424 from Abcam
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Anti-MRPL41 antibody - N-terminal - ab171541 from Abcam
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa7-36, AP) - LS-C237786 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa7-36, Biotin) - LS-C237788 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa7-36, APC) - LS-C237787 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa7-36, FITC) - LS-C237790 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa80-129) - LS-C152177 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa7-36, PE) - LS-C237791 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa7-36) - LS-C329848 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa7-36, Azide-free, HRP) - LS-C248849 from LifeSpan Bioscience
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Anti-TP53I3 / PIG3 Antibody (Leu265) - LS-C176823 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa8-36) - LS-C158302 from LifeSpan Bioscience
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Anti-MRPL41 / PIG3 / BMRP Antibody (aa81-130) - LS-C199276 from LifeSpan Bioscience
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MRPL41 Antibody - NBP1-88570 from Novus Biologicals
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PIG3 Antibody - NBP1-33237 from Novus Biologicals
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PIG3 Antibody (3B11) - NBP2-01301 from Novus Biologicals
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PIG3 Antibody - NBP1-87275 from Novus Biologicals
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PIG3 Antibody - NBP1-87274 from Novus Biologicals
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MRPL41 Antibody - 45470002 from Novus Biologicals
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