Gene Symbol | MRPL41 |
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Entrez Gene | 64975 |
Alt Symbol | BMRP, MRP-L27, MRPL27, PIG3, RPML27 |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial ribosomal protein L41 |
Other Description | 39S ribosomal protein L27 homolog|39S ribosomal protein L41, mitochondrial|L41mt|MRP-L27 homolog|MRP-L41|bcl-2-interacting mitochondrial ribosomal protein L41|cell proliferation-inducing gene 3 protein|proliferation-inducing gene 3 |
Swissprots | Q96Q49 Q8IXM3 |
Accessions | BAB54952 EAW88399 Q8IXM3 AI091177 AY232291 AAP69986 BC040035 AAH40035 BM919526 NM_032477 NP_115866 |
Function | Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. {ECO:0000269|PubMed:16024796, ECO:0000269|PubMed:16256947}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:16024796}. |
Tissue Specificity | Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level). {ECO:0000269|PubMed:15547950}. |
Human MRPL41 full length protein - ab163907 from Abcam
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MRPL41 / PIG3 / BMRP Antibody Blocking Peptide - LS-E2203 from LifeSpan Bioscience
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MRPL41 / PIG3 / BMRP Antibody Blocking Peptide - LS-E24112 from LifeSpan Bioscience
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Recombinant Human MRPL41 Protein - H00064975-P01 from Novus Biologicals
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MRPL41-Antibody-N-term-Blocking-Peptide - BP13125a from Abgent, a WuXi AppTec company
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PIG3 Protein - GTX111926-pro from GeneTex
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PIG3 (His Tag) protein - orb171587 from Biorbyt
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MRPL41 - H00064975-P01-10 from Acris Antibodies
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MRPL41 - H00064975-P01-25 from Acris Antibodies
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MRPL41 fusion protein - ag5476 from Proteintech Group
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Recombinant Human MRPL41 - MRPL41-1094H from Creative Biomart
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TP53I3 1-332aa - CMB-405 from Reagent Proteins
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Recombinant Human 39S ribosomal protein L41, mitochondrial(MRPL41) - CSB-YP811620HU CSB-EP811620HU CSB-BP811620HU CSB-MP811620HU from Cusabio
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MRPL41 - TP308136 from Acris Antibodies
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39S ribosomal protein L41, mitochondrial (MRPL41), Recombinant Protein - MBS1353014 from MyBioSource
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MRPL41 Recombinant Protein Antigen - NBP1-87553PEP from Novus Biologicals
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MRPL41 Recombinant Protein Antigen - NBP1-88571PEP from Novus Biologicals
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MRPL41 Recombinant Protein Antigen - NBP1-88570PEP from Novus Biologicals
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MRPL41 Blocking Peptide - abx061079 from Abbexa
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MRPL41 Peptide, Human - M34GP09750H from Creative Peptides
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MRPL41 Blocking Peptide - CBP4992 from Cohesion Biosciences
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MRPL41 peptide - orb319138 from Biorbyt
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