Gene Symbol | CCKAR |
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Entrez Gene | 886 |
Alt Symbol | CCK-A, CCK1-R, CCK1R, CCKRA |
Species | Human |
Gene Type | protein-coding |
Description | cholecystokinin A receptor |
Other Description | CCK-A receptor|CCK-AR|cholecystokinin receptor type A|cholecystokinin type-A receptor|cholecystokinin-1 receptor |
Swissprots | B2R9Z5 P32238 |
Accessions | AAA91123 BAA90879 EAW92850 P32238 AK313978 BAG36692 AY322549 AAP84362 BC074987 AAH74987 L13605 AAA35659 L19315 AAA02819 NM_000730 NP_000721 |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Pancreatic secretion, Neuroactive ligand-receptor interaction |
Human CCKAR peptide - ab42262 from Abcam
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E28715 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E28716 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E29355 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E29359 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E6602 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E26211 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E25884 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E23382 from LifeSpan Bioscience
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CCKAR / CCK1R Antibody Blocking Peptide - LS-E23381 from LifeSpan Bioscience
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CCKAR-AntibodyCenter-Blocking-peptide - BP19386c from Abgent, a WuXi AppTec company
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CCKAR blocking peptide - GTX89386-PEP from GeneTex
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Cckar Immunizing peptide - orb17928 from Biorbyt
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Goat anti CCKAR antibody Immunizing peptide - orb16787 from Biorbyt
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CCKAR Peptide - AC21-0713-P from Abcore
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CCKAR Peptide - 45-377P from ProSci
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CCKAR fusion protein - Ag12615 from Proteintech Group
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Recombinant Human CCKAR, His-tagged - CCKAR-10831H from Creative Biomart
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Recombinant Cholecystokinin A Receptor (CCKAR) - RPA104Hu01 from Uscn Life Science Inc.
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Recombinant Cholecystokinin A Receptor (CCKAR) - RPA104Mu01 from Uscn Life Science Inc.
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Recombinant Cholecystokinin A Receptor (CCKAR) - RPA104Mu02 from Uscn Life Science Inc.
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Recombinant Cholecystokinin A Receptor (CCKAR) - RPA104Ra01 from Uscn Life Science Inc.
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Recombinant Cholecystokinin A Receptor (CCKAR) - RPA104Gu01 from Uscn Life Science Inc.
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Recombinant Cholecystokinin A Receptor (CCKAR) - RPA104Rb01 from Uscn Life Science Inc.
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Recombinant Cholecystokinin A Receptor (CCKAR) - RPA104Ca01 from Uscn Life Science Inc.
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