Gene Symbol | CCKAR |
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Entrez Gene | 886 |
Alt Symbol | CCK-A, CCK1-R, CCK1R, CCKRA |
Species | Human |
Gene Type | protein-coding |
Description | cholecystokinin A receptor |
Other Description | CCK-A receptor|CCK-AR|cholecystokinin receptor type A|cholecystokinin type-A receptor|cholecystokinin-1 receptor |
Swissprots | B2R9Z5 P32238 |
Accessions | AAA91123 BAA90879 EAW92850 P32238 AK313978 BAG36692 AY322549 AAP84362 BC074987 AAH74987 L13605 AAA35659 L19315 AAA02819 NM_000730 NP_000721 |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Pancreatic secretion, Neuroactive ligand-receptor interaction |
CCK-AR (F-6) - sc-514303 from Santa Cruz Biotechnology
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CCK-AR (N-20) - sc-16172 from Santa Cruz Biotechnology
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CCK-AR (H-60) - sc-33220 from Santa Cruz Biotechnology
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CCK-AR (G-17) - sc-16173 from Santa Cruz Biotechnology
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Anti-CCKAR antibody - ab77269 from Abcam
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Anti-CCKAR antibody - ab75153 from Abcam
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Anti-CCKAR antibody - ab115287 from Abcam
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Anti-CCKAR antibody - C-terminal - ab140805 from Abcam
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Anti-CCKAR / CCK1R Antibody (aa170-183) - LS-C54623 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody - LS-C35919 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (C-Terminus) - LS-C22102 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa197-210) - LS-C89020 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa180-195) - LS-C128131 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa180-195) - LS-C128132 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa197-210) - LS-C128134 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (C-Terminus) - LS-C193714 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (C-Terminus) - LS-C202769 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa227-257, AP) - LS-C253733 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa242-291) - LS-C151628 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa227-257, APC) - LS-C253734 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa227-257, FITC) - LS-C253735 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa227-257, Biotin) - LS-C253736 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa215-264) - LS-C120637 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa227-257, PE) - LS-C253738 from LifeSpan Bioscience
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Anti-CCKAR / CCK1R Antibody (aa227-257, Azide-free, HRP) - LS-C253737 from LifeSpan Bioscience
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