Mgmt

Gene Symbol	Mgmt
Entrez Gene	17314
Alt Symbol	AGT, AI267024, Agat
Species	Mouse
Gene Type	protein-coding
Description	O-6-methylguanine-DNA methyltransferase
Other Description	6-O-methylguanine-DNA methyltransferase|O-6-alkylguanine-DNA alkyltransferase|O-6-methylguanine-DNA-alkyltransferase|methylated-DNA--protein-cysteine methyltransferase
Swissprots	P26187 Q54A49
Accessions	EDL17816 EDL17817 EDL17818 P26187 AB092489 BAC16763 AB092490 BAC16764 AK090389 BC031888 AAH31888 BC096557 AAH96557 BY344992 M84524 AAA37126 XM_006507405 XP_006507468 XM_006507406 XP_006507469 XM_006507407 XP_006507470 XM_006507408 XP_006507471 XM_006507409 XP_006507472 XM_006507410 XP_006507473 NM_008598 NP_032624
Function	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Subcellular Location	Nucleus {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

MGMT (M-15) - sc-8827 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-MGMT antibody - ab63930 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MGMT Antibody (300008) - MAB3299 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Rat Clonality Monoclonal Clone 300008

MGMT Antibody - AF3299 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

MGMT antibody - 70R-12116 from Fitzgerald Prices $335.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

anti-MGMT antibody - ARG20518 from Arigo Biolaboratories Host Rabbit Clonality Polyclonal

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