| Gene Symbol | Mgmt |
|---|---|
| Entrez Gene | 17314 |
| Alt Symbol | AGT, AI267024, Agat |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | O-6-methylguanine-DNA methyltransferase |
| Other Description | 6-O-methylguanine-DNA methyltransferase|O-6-alkylguanine-DNA alkyltransferase|O-6-methylguanine-DNA-alkyltransferase|methylated-DNA--protein-cysteine methyltransferase |
| Swissprots | P26187 Q54A49 |
| Accessions | EDL17816 EDL17817 EDL17818 P26187 AB092489 BAC16763 AB092490 BAC16764 AK090389 BC031888 AAH31888 BC096557 AAH96557 BY344992 M84524 AAA37126 XM_006507405 XP_006507468 XM_006507406 XP_006507469 XM_006507407 XP_006507470 XM_006507408 XP_006507471 XM_006507409 XP_006507472 XM_006507410 XP_006507473 NM_008598 NP_032624 |
| Function | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
| Subcellular Location | Nucleus {ECO:0000305}. |
Methylated-DNA--protein-cysteine methyltransferase, Mgmt, Mouse, ELISA Kit - E2027m from ARP American Research Products
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Mouse MGMT ELISA Kit - MM0272 from NeoScientific
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Mouse O-6-Methylguanine DNA Methyltransferase ELISA - E03M0265 from BlueGene Biotech
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Mouse Mgmt ELISA Kit - E060026 from Biobool
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MGMT ELISA Kit (Mouse) (OKEH05264) - OKEH05264 from Aviva Systems Biology
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Mouse MGMT ELISA Kit - EMM0272 from ABclonal
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Methylated-DNA--protein-cysteine methyltransferase, ELISA Kit - MBS2880595 from MyBioSource
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