HGSNAT

Gene Symbol HGSNAT
Entrez Gene 138050
Alt Symbol HGNAT, MPS3C, TMEM76
Species Human
Gene Type protein-coding
Description heparan-alpha-glucosaminide N-acetyltransferase
Other Description transmembrane protein 76
Swissprots B4E2V0 Q68CP4
Accessions Q68CP4 AK025895 BAB15273 AK057293 BAB71412 AK074839 AK304441 BAG65262 AK308922 AL355714 AL832870 BC012452 AAH12452 BC042037 AAH42037 BC050672 BC056149 BE327420 CR457352 CAG33633 CR749838 CAH18694 DA395558 DB128369 XM_005273409 XP_005273466 XM_005273410 XP_005273467 XM_005273411 XP_005273468 XM_005273412 XP_005273469 NM_152419 NP_689632
Function Lysosomal acetyltransferase that acetylates the non- reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase. {ECO:0000269|PubMed:16960811, ECO:0000269|PubMed:17033958, ECO:0000269|PubMed:19823584, ECO:0000269|PubMed:20650889}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:16960811, ECO:0000269|PubMed:17033958, ECO:0000269|PubMed:17897319}; Multi-pass membrane protein {ECO:0000269|PubMed:16960811, ECO:0000269|PubMed:17033958, ECO:0000269|PubMed:17897319}. Note=Colocalizes with the lysosomal marker LAMP2. The signal peptide is not cleaved upon translocation into the endoplasmic reticulum; the precursor is probably targeted to the lysosomes via the adapter protein complex-mediated pathway that involves tyrosine- and/or dileucine-based conserved amino acid motifs in the last C-terminus 16-amino acid domain.
Tissue Specificity Widely expressed, with highest level in leukocytes, heart, liver, skeletal muscle, lung, placenta and liver. {ECO:0000269|PubMed:16960811, ECO:0000269|PubMed:17033958}.
Top Pathways Lysosome, Glycosaminoglycan degradation

HGSNAT (S-18) - sc-82625 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HGSNAT (S-18): sc-82625. Western blot analysis of HGSNAT expression in HeLa whole cell lysate.

HGSNAT (K-15) - sc-82623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HGSNAT antibody - N-terminal - ab178393 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HGSNAT antibody - N-terminal (ab178393) at 1 µg/ml + HepG2 whole cell lysates at 10 µg

Anti-HGSNAT Antibody (aa563-612) - LS-C152073 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HGSNAT antibody Western Blot of OVCAR-3.

Anti-HGSNAT Antibody (N-Terminus) - LS-C186779 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human HepG2. HGSNAT antibody dilution 1.0 ug/ml.

HGSNAT Antibody - NBP1-81990 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: HGSNAT Antibody [NBP1-81990] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

Anti-HGSNAT antibody produced in rabbit - HPA029578 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HGSNAT: <B>Cat. No. HPA029578</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

HGSNAT Antibody - C-terminal region (ARP65767_P050) - ARP65767_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - N-terminal region (ARP65768_P050) - ARP65768_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HGSNAT antibody - 70R-17732 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

HGSNAT antibody - 12399-1-AP from Proteintech Group

Prices $259.00
Sizes 32 μg/150 μl
Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - EPP13915 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
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Rabbit Anti-Human HGSNAT Polyclonal Antibody - DPABH-12770 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

HGSNAT, Polyclonal Antibody - MBS2519367 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

HGSNAT antibody - TA337878 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
WB Suggested Anti-HGSNAT Antibody; Titration: 1.0 ug/ml; Positive Control: OVCAR-3 Whole Cell HGSNAT is supported by BioGPS gene expression data to be expressed in OVCAR3

HGSNAT antibody - TA337879 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit; Target Name: HGSNAT; Sample Tissue: HepG2 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml HGSNAT is supported by BioGPS gene expression data to be expressed in HepG2

Anti-HGSNAT Antibody A05564 - A05564 from Boster Bio

Prices $299.00
Sizes 1
Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - C-terminal region : Biotin (ARP65767_P050-Biotin) - ARP65767_P050-Biotin from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - C-terminal region : FITC (ARP65767_P050-FITC) - ARP65767_P050-FITC from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - C-terminal region : HRP (ARP65767_P050-HRP) - ARP65767_P050-HRP from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - N-terminal region : Biotin (ARP65768_P050-Biotin) - ARP65768_P050-Biotin from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - N-terminal region : FITC (ARP65768_P050-FITC) - ARP65768_P050-FITC from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - N-terminal region : HRP (ARP65768_P050-HRP) - ARP65768_P050-HRP from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

HGSNAT Antibody - N-terminal region (ARP82073_P050) - ARP82073_P050 from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

Anti-HGSNAT Antibody (aa563-612, Biotin) - LS-C473469 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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