Gene Symbol | GLCE |
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Entrez Gene | 26035 |
Alt Symbol | HSEPI |
Species | Human |
Gene Type | protein-coding |
Description | glucuronic acid epimerase |
Other Description | D-glucuronyl C5-epimerase|UDP-glucuronic acid epimerase|glucuronyl C5-epimerase|heparan sulfate C5-epimerase|heparan sulfate epimerase|heparin/heparan sulfate-glucuronic acid C5-epimerase|heparin/heparan sulfate:glucuronic acid C5-epimerase|heparosan-N-sulfate-glucuronate 5-epimerase |
Swissprots | O94923 Q6GUQ2 |
Accessions | EAW77837 O94923 AA393928 AB020643 BAA74859 AK002188 BAG51026 AY635582 AAT48654 BC026096 BC160046 AAI60046 N41364 W87397 XM_005254298 XP_005254355 XM_005254299 XP_005254356 NM_015554 NP_056369 |
Function | Converts D-glucuronic acid residues adjacent to N- sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins. {ECO:0000269|PubMed:20118238}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
GLCE (K-13) - sc-162869 from Santa Cruz Biotechnology
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GLCE (S-15) - sc-162870 from Santa Cruz Biotechnology
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Anti-Glucuronic Acid Epimerase antibody - ab68714 from Abcam
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Anti-GLCE Antibody - LS-C308075 from LifeSpan Bioscience
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Anti-GLCE Antibody - LS-C310492 from LifeSpan Bioscience
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Anti-GLCE Antibody (FITC) - LS-C318573 from LifeSpan Bioscience
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Anti-GLCE Antibody (HRP) - LS-C318574 from LifeSpan Bioscience
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Anti-GLCE Antibody (Biotin) - LS-C318575 from LifeSpan Bioscience
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Anti-GLCE Antibody - LS-C318572 from LifeSpan Bioscience
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Glucuronic Acid Epimerase Antibody - NBP2-31985 from Novus Biologicals
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Glucuronic Acid Epimerase Antibody - NBP2-31872 from Novus Biologicals
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Glucuronic Acid Epimerase Antibody - H00026035-B01P from Novus Biologicals
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Glucuronic Acid Epimerase Antibody - H00026035-D01 from Novus Biologicals
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Anti-GLCE antibody produced in rabbit - HPA040481 from Sigma-Aldrich
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Anti-GLCE antibody produced in rabbit - HPA048216 from Sigma-Aldrich
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Anti-GLCE antibody produced in mouse - SAB1401618 from Sigma-Aldrich
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Anti -GLCE (KIAA0836, D-glucuronyl C5-epimerase, Heparan Sulfate C5-epimerase,Heparin/Heparan Sulfate:Glucuronic Acid C5-epimerase, Heparosan-N-sulfate-glucuronate5-epimerase) - 127340 from USBiological Life Science
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Anti -GLCE (KIAA0836, D-glucuronyl C5-epimerase, Heparan Sulfate C5-epimerase,Heparin/Heparan Sulfate:Glucuronic Acid C5-epimerase, Heparosan-N-sulfate-glucuronate5-epimerase) - 127341 from USBiological Life Science
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D-glucuronyl C5-epimerasel Antibody - abx109723 from Abbexa
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D-glucuronyl C5-epimerasel Antibody (Biotin) - abx105341 from Abbexa
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D-glucuronyl C5-epimerasel Antibody (FITC) - abx106760 from Abbexa
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D-glucuronyl C5-epimerasel Antibody (HRP) - abx108179 from Abbexa
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GLCE antibody - H00026035-B01P from Acris Antibodies
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GLCE antibody - H00026035-D01 from Acris Antibodies
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GLCE, Polyclonal Antibody - MBS6001202 from MyBioSource
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