Gene Symbol | GLCE |
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Entrez Gene | 26035 |
Alt Symbol | HSEPI |
Species | Human |
Gene Type | protein-coding |
Description | glucuronic acid epimerase |
Other Description | D-glucuronyl C5-epimerase|UDP-glucuronic acid epimerase|glucuronyl C5-epimerase|heparan sulfate C5-epimerase|heparan sulfate epimerase|heparin/heparan sulfate-glucuronic acid C5-epimerase|heparin/heparan sulfate:glucuronic acid C5-epimerase|heparosan-N-sulfate-glucuronate 5-epimerase |
Swissprots | O94923 Q6GUQ2 |
Accessions | EAW77837 O94923 AA393928 AB020643 BAA74859 AK002188 BAG51026 AY635582 AAT48654 BC026096 BC160046 AAI60046 N41364 W87397 XM_005254298 XP_005254355 XM_005254299 XP_005254356 NM_015554 NP_056369 |
Function | Converts D-glucuronic acid residues adjacent to N- sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins. {ECO:0000269|PubMed:20118238}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
Human Glucuronic Acid Epimerase full length protein - ab161879 from Abcam
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Recombinant Human Glucuronic Acid Epimerase Protein - H00026035-P01 from Novus Biologicals
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GLCE-Antibody-Center-Blocking-Peptide - BP4927c from Abgent, a WuXi AppTec company
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Human GLCE protein - orb244232 from Biorbyt
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GLCE - H00026035-P01 from Acris Antibodies
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Recombinant Glucuronic Acid Epimerase (GLCE) - RPJ028Ra01 from Uscn Life Science Inc.
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Recombinant Human D-glucuronyl C5-epimerase(GLCE) - CSB-YP009492HU CSB-BP009492HU CSB-MP009492HU from Cusabio
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Recombinant human D-glucuronyl C5-epimerase - CSB-EP009492HU from Cusabio
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Glucuronic Acid Epimerase Protein - NBP2-31985PEP from Novus Biologicals
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Glucuronic Acid Epimerase Recombinant Protein Antigen - NBP2-31872PEP from Novus Biologicals
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GLCE Peptide, Human - M34GP06309H from Creative Peptides
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GLCE Recombinant Protein (OPCA01617) - OPCA01617 from Aviva Systems Biology
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Human D-glucuronyl C5-epimerase protein - orb6949 from Biorbyt
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Recombinant human D-glucuronyl C5-epimerase - AP70341 from Signalway Antibody
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D-glucuronyl C5-epimerase, Recombinant Protein - MBS1149096 from MyBioSource
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D-glucuronyl C5-epimerase, Recombinant Protein - MBS9420273 from MyBioSource
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D-glucuronyl C5-epimerase (GLCE), Recombinant Protein - MBS7042812 from MyBioSource
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Recombinant Human GLCE Protein (29-617 aa), His-tagged - GLCE-525H from Creative Biomart
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