ITGAM

Gene Symbol	ITGAM
Entrez Gene	3684
Alt Symbol	CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Species	Human
Gene Type	protein-coding
Description	integrin, alpha M (complement component 3 receptor 3 subunit)
Other Description	CD11 antigen-like family member B|CR-3 alpha chain|antigen CD11b (p170)|cell surface glycoprotein MAC-1 subunit alpha|integrin alpha-M|leukocyte adhesion receptor MO1|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit
Swissprots	Q4VAK0 P11215 Q4VAK2 Q4VAK1
Accessions	AAA51960 AAA58410 AAB24821 CCF76944 EAW52143 EAW52144 P11215 AA436312 AK057856 AK127637 BAG54538 AY187247 AY187248 BC096346 AAH96346 BC096347 AAH96347 BC096348 AAH96348 BC099660 AAH99660 BM194233 J03925 AAA59544 J04145 AAA59903 M18044 AAA59491 XM_006721045 XP_006721108 XM_011545850 XP_011544152 XM_011545851 XP_011544153 XR_950796 NM_000632 NP_000623 NM_001145808 NP_001139280
Function	Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Predominantly expressed in monocytes and granulocytes.
Top Pathways	Staphylococcus aureus infection, Legionellosis, Tuberculosis, Rap1 signaling pathway, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SimpleChIP ® Human CD11b Promoter Primers - 14271 from Cell Signaling Technology Category ChIP Kit Prices $102.00 Sizes 500 µl (250 PCR reactions)

Rat ITGAM / CD11b ELISA Kit (Sandwich ELISA) - LS-F4904 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.115 ng/ml Range 0.313-20 ng/ml

Human ITGAM / CD11b ELISA Kit (Sandwich ELISA) - LS-F9298 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 13.3 pg/ml Range 0.313-20 ng/ml

Human ITGAM / CD11b ELISA Kit (Sandwich ELISA) - LS-F11850 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.313-20 ng/ml

Integrin αM, ITG/CD11b, Human, ELISA Kit - YHB1660Hu from ARP American Research Products Category ELISA Kit

Integrin Alpha M (ITGaM), Human, ELISA Kit - SEB685Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.125ng/mL Range 0.312-20ng/mL

Integrin alpha M, ITG/CD11b, Human, ELISA Kit - CSB-E11638h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.2 ng/ml Range 0.78 ng/ml -50 ng/ml

Integrin alpha-M, ITGAM, Human, ELISA Kit - E1685h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Human ITG/CD11b ELISA Kit - HI0418 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Guinea Pig ITG/CD11b ELISA Kit - GI0418 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Canine ITG/CD11b ELISA Kit - CI0418 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Goat ITG/CD11b ELISA Kit - GTI0418 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rabbit ITG/CD11b ELISA Kit - RTI0418 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ITG/CD11b ELISA Kit - AI0418 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Integrin Alpha M, ELISA Kit - MBS055359 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS058433 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS055875 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS062021 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS055634 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS065888 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS068195 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS103779 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS096105 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS086890 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin Alpha M, ELISA Kit - MBS056175 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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