ITGAM

Gene Symbol ITGAM
Entrez Gene 3684
Alt Symbol CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Species Human
Gene Type protein-coding
Description integrin, alpha M (complement component 3 receptor 3 subunit)
Other Description CD11 antigen-like family member B|CR-3 alpha chain|antigen CD11b (p170)|cell surface glycoprotein MAC-1 subunit alpha|integrin alpha-M|leukocyte adhesion receptor MO1|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit
Swissprots Q4VAK0 P11215 Q4VAK2 Q4VAK1
Accessions AAA51960 AAA58410 AAB24821 CCF76944 EAW52143 EAW52144 P11215 AA436312 AK057856 AK127637 BAG54538 AY187247 AY187248 BC096346 AAH96346 BC096347 AAH96347 BC096348 AAH96348 BC099660 AAH99660 BM194233 J03925 AAA59544 J04145 AAA59903 M18044 AAA59491 XM_006721045 XP_006721108 XM_011545850 XP_011544152 XM_011545851 XP_011544153 XR_950796 NM_000632 NP_000623 NM_001145808 NP_001139280
Function Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Predominantly expressed in monocytes and granulocytes.
Top Pathways Staphylococcus aureus infection, Legionellosis, Tuberculosis, Rap1 signaling pathway, Pertussis

Integrin αM CRISPR/Cas9 KO Plasmid (h) - sc-400563 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM HDR Plasmid (h) - sc-400563-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM Double Nickase Plasmid (h) - sc-400563-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM Double Nickase Plasmid (h2) - sc-400563-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM CRISPR Activation Plasmid (h) - sc-400563-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM CRISPR Activation Plasmid (h2) - sc-400563-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM Lentiviral Activation Particles (h) - sc-400563-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM Lentiviral Activation Particles (h2) - sc-400563-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αM siRNA (h) - sc-37261 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin αM shRNA Plasmid (h) - sc-37261-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin αM shRNA (h) Lentiviral Particles - sc-37261-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU048811 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1535 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1536 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1535 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1536 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08462 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08462

ITGAM siRNA (Human) - CRH2474 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD11b RNAi - H00003684-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ITGAM - MBS8208773 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ITGAM (NM_000632.3) - SHH321305 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ITGAM(NM_000632.3) - SHL183162 from Creative biogene

Category siRNA
Species Reactivities Human

Human ITGAM siRNA - orb262976 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ITGAM shRNA Plasmid (Human) - CHH2474 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ITGAM miRNA 3'UTR clone - MiUTR1H-05030 from Creative biogene

Species Reactivities Human
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