ITGAM

Gene Symbol	ITGAM
Entrez Gene	3684
Alt Symbol	CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Species	Human
Gene Type	protein-coding
Description	integrin, alpha M (complement component 3 receptor 3 subunit)
Other Description	CD11 antigen-like family member B|CR-3 alpha chain|antigen CD11b (p170)|cell surface glycoprotein MAC-1 subunit alpha|integrin alpha-M|leukocyte adhesion receptor MO1|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit
Swissprots	Q4VAK0 P11215 Q4VAK2 Q4VAK1
Accessions	AAA51960 AAA58410 AAB24821 CCF76944 EAW52143 EAW52144 P11215 AA436312 AK057856 AK127637 BAG54538 AY187247 AY187248 BC096346 AAH96346 BC096347 AAH96347 BC096348 AAH96348 BC099660 AAH99660 BM194233 J03925 AAA59544 J04145 AAA59903 M18044 AAA59491 XM_006721045 XP_006721108 XM_011545850 XP_011544152 XM_011545851 XP_011544153 XR_950796 NM_000632 NP_000623 NM_001145808 NP_001139280
Function	Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Predominantly expressed in monocytes and granulocytes.
Top Pathways	Staphylococcus aureus infection, Legionellosis, Tuberculosis, Rap1 signaling pathway, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD11b/Integrin alpha M (NP_001139280) VersaClone cDNA - RDC0847 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

ITGAM - MBS1270802 from MyBioSource Species Human Accession BC096346

Human ITGAM cDNA clone(NM_001145808.1) - CDFH009441 from Creative Biomart Species Human Accession NM_001145808.1

Human ITGAM ORF Clone(NM_001145808.1) - CDCR353080 from Creative Biomart Species Human Accession NM_001145808.1

Human ITGAM ORF Clone(NM_001145808.1) - CDCR353081 from Creative Biomart Species Human Accession NM_001145808.1

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone in cloning vector - HG10494-M from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, N-His tag - HG10494-NH from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10494-NF from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10494-NM from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10494-CF from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, C-HA tag - HG10494-CY from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, N-HA tag - HG10494-NY from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10494-CM from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10494-M-F from Sino Biological Species Human

Human Integrin alpha M Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - HG10494-CH from Sino Biological Species Human Accession NM_000632.3

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid - HG10494-UT from Sino Biological Species Human

Human Integrin alpha M ORF clone(NM_000632.3) - CDCL184941 from Creative biogene Species Human

Human ITGAM ORF Clone(NM_001145808.1) - CDCR353080 from Creative biogene Species Human

Human ITGAM ORF Clone (BC096346) - CDCS405806 from Creative biogene Species Human Accession P11215

Human ITGAM cDNA Clone(NM_001145808.1) - CDFH009441 from Creative biogene Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10494-ACR from Sino Biological Species Human

Human CD11b/ITGAM/Integrin alpha M Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10494-ACG from Sino Biological Species Human

Mouse CD11b/Integrin alpha M (NP_032427) VersaClone cDNA - RDC1740 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

Search more