HAVCR2

Gene Symbol HAVCR2
Entrez Gene 84868
Alt Symbol HAVcr-2, KIM-3, TIM3, TIMD-3, TIMD3, Tim-3
Species Human
Gene Type protein-coding
Description hepatitis A virus cellular receptor 2
Other Description T cell immunoglobulin mucin 3|T cell immunoglobulin mucin-3|T-cell immunoglobulin and mucin domain-containing protein 3|T-cell immunoglobulin mucin family member 3|T-cell immunoglobulin mucin receptor 3|T-cell membrane protein 3|kidney injury molecule-3
Swissprots Q96K94 Q8WW60 Q8TDQ0 B2RAY2
Accessions CAH05307 EAW61613 EAW61614 Q8TDQ0 AB924452 BAQ00263 AF251707 AAM19100 AF450242 AAL65157 AF450243 AAL65158 AK027334 BAB55044 AK130144 AK314406 BAG37029 AY069944 AAL55401 BC020843 AAH20843 BC063431 AAH63431 BP291914 HQ448118 ADQ32599 JX049979 AFO66593 NM_032782 NP_116171
Function Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9. {ECO:0000269|PubMed:14556005, ECO:0000269|PubMed:16286920}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity T-helper type 1 lymphocyte (Th1)-specific.

TIM-3 (E-18) - sc-30326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TIM-3 (H-191) - sc-292389 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TIM-3 (H-191): sc-292389. Western blot analysis of TIM-3 expression in human liver tissue extract.

TIM-3 (N-16) - sc-30325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TIM 3 antibody - ab185703 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TIM 3 antibody (ab185703) at 1/500 dilutionLane 1 : BT474 cell extractLane 2 : PC3 cell extractLane 3 : U937 cell extractLane 4 : HepG2 cell extractLane 5 : 293T cell extractLane 6 : mouse spleen extractLane 7 : mouse lung extractLane 8 : mouse brain extract

Anti-TIM 3 antibody - ab47997 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
ICC/IF image of ab47997 stained Hek293 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 0.3M glycine in 0.1% PBS-Tween (no animal serum) for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab47997 at 10µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Alexa Fluor® 488 donkey anti- goat (ab150133) IgG used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-TIM 3 antibody - ab156143 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TIM 3 antibody (ab156143) at 1/100 dilution + T47D cell lysate at 35 µg

Anti-TIM 3 antibody [F38-2E2] - ab104709 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone F38-2E2
Cell surface staining of unstimulated (A) and Con A stimulated (B) Human PBMCs with 0.6 ug of purified Human TIM 3 antibody (Red) and mouse IgG1 isotype control (Green). A cell surface flow kit and PE-conjugated secondary antibody were used for this test. Cells were not fixed for testing.

Anti-TIM 3 antibody [F38-2E2], prediluted (Allophycocyanin) - ab155379 from Abcam

Prices $376.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone F38-2E2
Flow Cytometric analysis of unstimulated (left) or anti-Human CD3 and anti-Human CD28 stimulated (right) normal Human peripheral blood cells with anti-Human CD4 FITC and ab155379 at 0.06 µg. Total viable cells, as determined by Fixable Viability Dye eFluor® 780, were used for analysis.

Anti-TIM 3 antibody [MM0936-14S23] - ab201626 from Abcam

Prices $359.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone MM0936-14S23

Anti-HAVCR2 / TIM-3 Antibody - LS-C18101 from LifeSpan Bioscience

Prices $405.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-HAVCR2 / TIM-3 Antibody - LS-C48728 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HAVCR2 / TIM-3 Antibody (clone 25F.1D6) - LS-C34598 from LifeSpan Bioscience

Prices $305.00
Sizes 250 µg
Host Rat
Clonality Monoclonal
Clone 25F.1D6

Anti-HAVCR2 / TIM-3 Antibody (aa225-236) - LS-C55594 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-HAVCR2 / TIM-3 Antibody (clone 25F.1D6, Biotin) - LS-C62963 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 25F.1D6

Anti-HAVCR2 / TIM-3 Antibody (clone 25F.1D6, PE) - LS-C62965 from LifeSpan Bioscience

Prices $285.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 25F.1D6

Anti-HAVCR2 / TIM-3 Antibody (clone 25F.1D6, FITC) - LS-C62964 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 25F.1D6

Anti-HAVCR2 / TIM-3 Antibody (aa100-200) - LS-C684 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TIM-3 in A) mouse and B) rat kidney cell lysate using antibody at 2 ug/ml.

Anti-HAVCR2 / TIM-3 Antibody (clone B8.2C12, PE) - LS-C148670 from LifeSpan Bioscience

Host Rat
Clonality Monoclonal
Clone B8.2C12

Anti-HAVCR2 / TIM-3 Antibody (clone B8.2C12, PE) - LS-C148669 from LifeSpan Bioscience

Host Rat
Clonality Monoclonal
Clone B8.2C12
Cell surface staining of mouse TIM-3 transfected and mock transfected CHO cells using LS-C148669 at 1 ug/10^6 cells.

Anti-HAVCR2 / TIM-3 Antibody (clone F38-2E2, APC) - LS-C107052 from LifeSpan Bioscience

Prices $265.00, $395.00
Sizes 25 tst, 100 tst
Host Mouse
Clonality Monoclonal
Clone F38-2E2
Staining of non-polarized (left) or Th1-polarized (right) normal human peripheral blood cells with FITC anti-human CD4 (RPA-T4) (LS-C106503) and APC anti-human TIM-3 (TIM3). Total viable cells were used for analysis.

Anti-HAVCR2 / TIM-3 Antibody (aa20-193, clone 11n191, PerCP) - LS-C184909 from LifeSpan Bioscience

Prices $575.00
Sizes 100 tst
Host Rat
Clonality Monoclonal
Clone 11n191

Anti-HAVCR2 / TIM-3 Antibody (clone F38-2E2) - LS-C148665 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone F38-2E2
Cell surface staining of unstimulated (A) and Con A stimulated (B) human PBMCs with 0.6 ug of purified human TIM-3 antibody (Red) and mouse IgG1 isotype control (Green),.

Anti-HAVCR2 / TIM-3 Antibody (aa201-250) - LS-C135489 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HAVCR2 / TIM 3 antibody LS-C135489 Western blot of Fetal Liver lysate.

Anti-HAVCR2 / TIM-3 Antibody (clone F38-2E2, PE) - LS-C148666 from LifeSpan Bioscience

Prices $385.00
Sizes 25 tst
Host Mouse
Clonality Monoclonal
Clone F38-2E2
Cell surface staining of Con A stimulated human PBMCs with 10 ul of PE-conjugated human TIM-3 antibody (Red) and mouse IgG1 isotype control (Green),.

Anti-HAVCR2 / TIM-3 Antibody (N-Terminus) - LS-C111043 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HAVCR2 / TIM 3 antibody LS-C111043 Western blot of OVCAR-3 cell lysate.
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