RNF169

Gene Symbol RNF169
Entrez Gene 254225
Alt Symbol -
Species Human
Gene Type protein-coding
Description ring finger protein 169
Other Description E3 ubiquitin-protein ligase RNF169
Swissprots Q8NCN4 Q6N015
Accessions EAW74947 Q8NCN4 AB082522 BAC02700 BC169205 AAI69205 BU735906 BX640750 CAE45858 DQ580376 DQ600280 XM_011544889 XP_011543191 XM_011544890 XP_011543192 NM_001098638 NP_001092108
Function Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin- protein ligase activity is not required for regulation of DSBs repair. {ECO:0000269|PubMed:22492721, ECO:0000269|PubMed:22733822, ECO:0000269|PubMed:22742833}.
Subcellular Location Nucleus, nucleoplasm {ECO:0000269|PubMed:22492721, ECO:0000269|PubMed:22733822, ECO:0000269|PubMed:22742833}. Note=Localizes to sites of double- strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products.

RNF169 CRISPR/Cas9 KO Plasmid (h) - sc-408708 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 HDR Plasmid (h) - sc-408708-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 Double Nickase Plasmid (h) - sc-408708-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 Double Nickase Plasmid (h2) - sc-408708-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 CRISPR Activation Plasmid (h) - sc-408708-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 CRISPR Activation Plasmid (h2) - sc-408708-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 Lentiviral Activation Particles (h) - sc-408708-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 Lentiviral Activation Particles (h2) - sc-408708-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF169 siRNA (h) - sc-96766 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RNF169 shRNA Plasmid (h) - sc-96766-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RNF169 shRNA (h) Lentiviral Particles - sc-96766-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RNF169 RNAi - H00254225-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RNF169 RNAi - H00254225-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU004991 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18401 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18401 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RNF169 siRNA (Human) - CRJ6674 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RNF169 RNAi - H00254225-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RNF169 - MBS8207617 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RNF169 (NM_001098638.1) - SHH396940 from Creative biogene

Category siRNA
Species Reactivities Human

Human RNF169 siRNA - orb277175 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RNF169 shRNA Plasmid (Human) - CHJ6674 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more