Pick1

Gene Symbol Pick1
Entrez Gene 18693
Alt Symbol Prkcabp
Species Mouse
Gene Type protein-coding
Description protein interacting with C kinase 1
Other Description PRKCA-binding protein|protein kinase C-alpha-binding protein|protein that interacts with C kinase 1
Swissprots Q62083 E9PY04
Accessions EDL04663 EDL04664 EDL04665 EDL04666 EDL04667 Q62083 AI385692 AI893973 AK050224 AK090155 BAC41117 AK162724 AK177140 BC023088 BC030363 BC030880 BC030912 BC040824 BC048788 AAH48788 BE652516 BU057774 BU698586 CA468666 CD363874 CK791908 Z46720 CAA86675 XM_006520603 XP_006520666 XM_006520604 XP_006520667 XM_006520605 XP_006520668 XM_006520606 XP_006520669 XM_006520607 XP_006520670 NM_001045558 NP_001039023 NM_008837 NP_032863
Function Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function. {ECO:0000269|PubMed:1497
Subcellular Location Cytoplasm, perinuclear region {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane {ECO:0000269|PubMed:24068808}; Lipid-anchor {ECO:0000269|PubMed:24068808}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Also membrane-associated, present at excitatory synapses. {ECO:0000250}.
Tissue Specificity Expressed in all tissues examined, with highest levels in brain and testes and lowest levels in lung.

PICK1 (C-20) - sc-9541 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PICK1 (C-20): sc-9541. Western blot analysis of PICK1 expression in rat (A) and mouse (B) brain tissue extracts.

Anti-PICK1 antibody - ab15001 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

PICK1 Antibody - NB120-3420 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PICK1 Antibody [NB120-3420] - Analysis of PICK1 from AtT20 cell lysate.

PICK1 Antibody (S20-8) - NBP1-49572 from Novus Biologicals

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S20-8
Western Blot: PICK1 Antibody (S20-8) [NBP1-49572] - Rat brain membrane tissues using a 1:1000 dilution.

PICK1 Antibody - abx104548 from Abbexa

Host Rabbit
Clonality Polyclonal

PICK1 antibody - SP5150P from Acris Antibodies

Prices $450.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunolocalization of PICK1 in CV1 cells transfected with both PICK1 and mGluR7a using SP5150P

Goat Anti-Human PICK1 - DS-PB-02335 from RayBiotech

Host Goat

Anti-PICK1 antibody - STJ71020 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

Anti-PICK1 (aa 1-18) polyclonal antibody - DPABH-27938 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

PICK1 Polyclonal Antibody - PA1-073 from Thermo Fisher Scientific

Prices $375.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot detection of PICK1 from AtT20 cell lysate using PA1-073.

PICK1 Polyclonal Antibody - PA5-18593 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot staining of Mouse brain lysate using PA5-18593 at a concentration of 1.0 ug/ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.

PICK1 Polyclonal Antibody - PA5-23015 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µl
Host Chicken
Clonality Polyclonal
PICK1 Antibody (PA5-23015) in IHC

Protein Interacting With Protein Kinase C Alpha 1 (PICK1), Polyclonal Antibody - MBS2016825 from MyBioSource

Prices $150.00, $290.00, $460.00
Sizes 20 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

PICK1 antibody - GTX15001 from GeneTex

Prices $289.00
Sizes 50 μl
Host Rabbit
Clonality Polyclonal

PICK1 antibody, Internal - GTX89265 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-PICK1 antibody, Internal used in Western blot. GTX89265

PICK1 antibody - TA309463 from Acris Antibodies

Prices $325.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S20-8
IHC analysis of Pick1 in frozen sections of mouse brain extract using TA309463.

Anti-PICK1 Goat Antibody - EB07467 from ARP American Research Products

Prices $315.00
Sizes 100 µg
Clonality Polyclonal

PICK1, Polyclonal Antibody - MBS611518 from MyBioSource

Prices $610.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more