Pick1

Gene Symbol Pick1
Entrez Gene 18693
Alt Symbol Prkcabp
Species Mouse
Gene Type protein-coding
Description protein interacting with C kinase 1
Other Description PRKCA-binding protein|protein kinase C-alpha-binding protein|protein that interacts with C kinase 1
Swissprots Q62083 E9PY04
Accessions EDL04663 EDL04664 EDL04665 EDL04666 EDL04667 Q62083 AI385692 AI893973 AK050224 AK090155 BAC41117 AK162724 AK177140 BC023088 BC030363 BC030880 BC030912 BC040824 BC048788 AAH48788 BE652516 BU057774 BU698586 CA468666 CD363874 CK791908 Z46720 CAA86675 XM_006520603 XP_006520666 XM_006520604 XP_006520667 XM_006520605 XP_006520668 XM_006520606 XP_006520669 XM_006520607 XP_006520670 NM_001045558 NP_001039023 NM_008837 NP_032863
Function Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function. {ECO:0000269|PubMed:1497
Subcellular Location Cytoplasm, perinuclear region {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane {ECO:0000269|PubMed:24068808}; Lipid-anchor {ECO:0000269|PubMed:24068808}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Also membrane-associated, present at excitatory synapses. {ECO:0000250}.
Tissue Specificity Expressed in all tissues examined, with highest levels in brain and testes and lowest levels in lung.

Mouse PICK1 Protein - abx068744 from Abbexa

Category Protein
Source E.coli
Species Mouse

Recombinant Protein Interacting With Protein Kinase C Alpha 1 (PICK1) - RPA931Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Protein Interacting With Protein Kinase C Alpha 1 (PICK1) - RPA931Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse PRKCA-binding protein(Pick1) - CSB-YP720285MO CSB-EP720285MO CSB-BP720285MO CSB-MP720285MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

PRKCA-binding protein (Pick1), Recombinant Protein - MBS1409956 from MyBioSource

Category Protein
Prices $1,190.00, $1,190.00, $1,410.00, $1,410.00, $1,915.00, $1,915.00, $2,380.00, $2,380.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

PICK1 Recombinant Protein (OPCD06163) - OPCD06163 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse

Protein Interacting With Protein Kinase C Alpha 1 (PICK1), Recombinant Protein - MBS2018326 from MyBioSource

Category Protein
Prices $195.00, $410.00, $635.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Mouse
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