PARD6A

Gene Symbol	PARD6A
Entrez Gene	50855
Alt Symbol	PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
Species	Human
Gene Type	protein-coding
Description	par-6 family cell polarity regulator alpha
Other Description	PAR-6 alpha|Tax-interacting protein 40|par-6 partitioning defective 6 homolog alpha|partitioning defective 6 homolog alpha|partitioning defective-6 homolog alpha|partitioning-defective protein 6|tax interaction protein 40
Swissprots	O14911 Q9NPB6 Q9NPJ7
Accessions	EAW83151 Q9NPB6 AB041642 BAB16105 AB043634 BAA96235 AF028827 AAB84252 AF252292 AAF71529 AF265565 AAF75548 AJ277095 CAB85490 BC015626 AAH15626 DQ893477 ABM84403 DQ896347 ABM87346 XM_005255977 XP_005256034 XM_011523095 XP_011521397 XM_011523096 XP_011521398 NM_001037281 NP_001032358 NM_016948 NP_058644
Function	Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. {ECO:0000269|PubMed:10873802}.
Subcellular Location	Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Note=Colocalizes with GTP- bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions.
Tissue Specificity	Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta.
Top Pathways	Tight junction, Endocytosis, Hippo signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-PARD6A-cDNA-Clone - DC04148 from Abgent, a WuXi AppTec company Prices $467.10 Sizes 10 µg Species Human Accession BC015626

PARD6A - MBS1277132 from MyBioSource Species Human Accession BC015626

Human PARD6A cDNA clone(NM_001037281.1) - CDFH013700 from Creative Biomart Species Human Accession NM_001037281.1

Human PARD6A ORF Clone(NM_001037281.1) - CDCR343419 from Creative Biomart Species Human Accession NM_001037281.1

Human PARD6A ORF Clone(NM_001037281.1) - CDCR343420 from Creative Biomart Species Human Accession NM_001037281.1

Human PARD6A ORF Clone(NM_001037281.1) - CDCR343421 from Creative Biomart Species Human Accession NM_001037281.1

Human PARD6A Gene ORF cDNA clone in cloning vector - HG14400-G from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, C-HA tag - HG14400-CY from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14400-NF from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14400-CF from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14400-NM from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14400-CM from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, N-His tag - HG14400-NH from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14400-ANG from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, N-HA tag - HG14400-NY from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14400-ACG from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, C-His tag - HG14400-CH from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14400-ACR from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14400-ANR from Sino Biological Species Human

Human PARD6A Gene ORF cDNA clone expression plasmid - HG14400-UT from Sino Biological Species Human

Human PARD6A ORF Clone(NM_001037281.1) - CDCR343419 from Creative biogene Species Human

Human PARD6A ORF clone (NM_016948.2) - CDCL145959 from Creative biogene Species Human

Human PARD6A ORF Clone (BC015626) - CDCS406893 from Creative biogene Species Human Accession Q9NPB6

Human PARD6A ORF clone (BC015626) - CDCB159105 from Creative biogene Species Human

Human PARD6A cDNA Clone(NM_001037281.1) - CDFH013700 from Creative biogene Species Human

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