NCF1

Gene Symbol	NCF1
Entrez Gene	653361
Alt Symbol	NCF1A, NOXO2, SH3PXD1A, p47phox
Species	Human
Gene Type	protein-coding
Description	neutrophil cytosolic factor 1
Other Description	47 kDa autosomal chronic granulomatous disease protein|47 kDa neutrophil oxidase factor|NADPH oxidase organizer 2|NCF-1|NCF-47K|SH3 and PX domain-containing protein 1A|neutrophil NADPH oxidase factor 1|neutrophil cytosol factor 1|neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)|nox organizer 2|nox-organizing protein 2|p47-phox
Swissprots	Q9UMU2 Q2PP07 A8K7S9 Q53FR5 Q9BXI8 A6NEH2 Q9UDV9 Q9BU90 O43842 Q9BXI7 P14598
Accessions	AAA60086 AAA60087 AAB95193 AAF34737 AAS07465 P14598 AF330625 AAK19516 AF330626 AAK19517 AK127905 BAG54596 AK223217 BAD96937 AK292094 BAF84783 AK316341 BAH14712 AK316552 BAG65630 AW204865 AW207763 BC002816 AAH02816 BC065731 AAH65731 DQ893150 ABM84076 DQ896445 ABM87444 GU215077 HQ447816 ADQ32300 U25793 AAA93232 XM_005250543 XP_005250600 XM_005250544 XP_005250601 XM_011516498 XP_011514800 XM_011516499 XP_011514801 XM_011516500 XP_011514802 XM_011516501 XP_011514803 XR_242262 XR_927515 NM_000265 NP_000256
Function	NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). {ECO:0000269|PubMed:19801500, ECO:0000269|PubMed:2547247, ECO:0000269|PubMed:2550933}.
Subcellular Location	Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity	Detected in peripheral blood monocytes and neutrophils (at protein level). {ECO:0000269|PubMed:2547247, ECO:0000269|PubMed:2550933}.
Top Pathways	Leukocyte transendothelial migration, Fc gamma R-mediated phagocytosis, Chemokine signaling pathway, Leishmaniasis, Phagosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NCF1 overexpression lysate - LY400103 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NCF1 293 Cell Lysate - 400191 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

NCF1 Overexpression Lysate (Native) - NBL1-13509 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NCF1 Over-expression Lysate Product - GWB-117D6B from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human NCF1 Knockdown Stable Cell Line - CSC-DC010181 from Creative biogene Category Cell Line Species Human

Search more