NCF1

Gene Symbol	NCF1
Entrez Gene	653361
Alt Symbol	NCF1A, NOXO2, SH3PXD1A, p47phox
Species	Human
Gene Type	protein-coding
Description	neutrophil cytosolic factor 1
Other Description	47 kDa autosomal chronic granulomatous disease protein|47 kDa neutrophil oxidase factor|NADPH oxidase organizer 2|NCF-1|NCF-47K|SH3 and PX domain-containing protein 1A|neutrophil NADPH oxidase factor 1|neutrophil cytosol factor 1|neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)|nox organizer 2|nox-organizing protein 2|p47-phox
Swissprots	Q9UMU2 Q2PP07 A8K7S9 Q53FR5 Q9BXI8 A6NEH2 Q9UDV9 Q9BU90 O43842 Q9BXI7 P14598
Accessions	AAA60086 AAA60087 AAB95193 AAF34737 AAS07465 P14598 AF330625 AAK19516 AF330626 AAK19517 AK127905 BAG54596 AK223217 BAD96937 AK292094 BAF84783 AK316341 BAH14712 AK316552 BAG65630 AW204865 AW207763 BC002816 AAH02816 BC065731 AAH65731 DQ893150 ABM84076 DQ896445 ABM87444 GU215077 HQ447816 ADQ32300 U25793 AAA93232 XM_005250543 XP_005250600 XM_005250544 XP_005250601 XM_011516498 XP_011514800 XM_011516499 XP_011514801 XM_011516500 XP_011514802 XM_011516501 XP_011514803 XR_242262 XR_927515 NM_000265 NP_000256
Function	NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). {ECO:0000269|PubMed:19801500, ECO:0000269|PubMed:2547247, ECO:0000269|PubMed:2550933}.
Subcellular Location	Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity	Detected in peripheral blood monocytes and neutrophils (at protein level). {ECO:0000269|PubMed:2547247, ECO:0000269|PubMed:2550933}.
Top Pathways	Leukocyte transendothelial migration, Fc gamma R-mediated phagocytosis, Chemokine signaling pathway, Leishmaniasis, Phagosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NCF1 full length protein - ab98054 from Abcam Category Protein Source E. coli Species Human

Human NCF1 peptide - ab22781 from Abcam Category Peptide Species Human

NCF1 / p47phox / p47 phox Antibody Blocking Peptide - LS-E25211 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCF1 / p47phox / p47 phox Antibody Blocking Peptide - LS-E8028 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCF1 / p47phox / p47 phox Antibody Blocking Peptide - LS-E27562 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NCF1 Protein - NBP1-45305 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E.coli Species Human

NCF1 Recombinant Protein - P3408 from Novus Biologicals Category Protein Prices $669.00 Sizes 50 µg Species Human

NCF1-Antibody-N-term-Blocking-peptide - BP5882a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NCF1 Protein (OPPA02336) - OPPA02336 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human Neutrophil Cytosolic Factor 1 protein - orb81229 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 2 μg, 10 μg Source E.coli Species Human

NCF1 peptide - orb218784 from Biorbyt Category Peptide Prices $357.00, $723.00 Sizes 1 mg, 5 mg Species Human, Mouse

NCF1 protein (His tag) - 80R-1415 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

NCF1 Peptide - AC21-0033-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NCF1 Peptide - AC21-2384-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NCF1 (1-390, His-tag) - AR09591PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

NCF1 (1-390, His-tag) - AR09591PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

NCF1 - P3408 from Acris Antibodies Category Protein Prices $580.00 Sizes 50 µg Species Human

Neutrophil Cytosolic Factor 1, Human Recombinant - 228-13091-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Neutrophil Cytosolic Factor 1 - 228-13091-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Neutrophil Cytosolic Factor 1 - 228-13091-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

NCF1, 1-390aa, Human, His tag, E.coli - 01-NCF1 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

NCF1 Peptide - 45-096P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

NCF1 fusion protein - Ag6026 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NCF1 fusion protein - ag6410 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human NCF1 Protein - BP003023-PRO-488 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

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