NCF1

Gene Symbol NCF1
Entrez Gene 653361
Alt Symbol NCF1A, NOXO2, SH3PXD1A, p47phox
Species Human
Gene Type protein-coding
Description neutrophil cytosolic factor 1
Other Description 47 kDa autosomal chronic granulomatous disease protein|47 kDa neutrophil oxidase factor|NADPH oxidase organizer 2|NCF-1|NCF-47K|SH3 and PX domain-containing protein 1A|neutrophil NADPH oxidase factor 1|neutrophil cytosol factor 1|neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)|nox organizer 2|nox-organizing protein 2|p47-phox
Swissprots Q9UMU2 Q2PP07 A8K7S9 Q53FR5 Q9BXI8 A6NEH2 Q9UDV9 Q9BU90 O43842 Q9BXI7 P14598
Accessions AAA60086 AAA60087 AAB95193 AAF34737 AAS07465 P14598 AF330625 AAK19516 AF330626 AAK19517 AK127905 BAG54596 AK223217 BAD96937 AK292094 BAF84783 AK316341 BAH14712 AK316552 BAG65630 AW204865 AW207763 BC002816 AAH02816 BC065731 AAH65731 DQ893150 ABM84076 DQ896445 ABM87444 GU215077 HQ447816 ADQ32300 U25793 AAA93232 XM_005250543 XP_005250600 XM_005250544 XP_005250601 XM_011516498 XP_011514800 XM_011516499 XP_011514801 XM_011516500 XP_011514802 XM_011516501 XP_011514803 XR_242262 XR_927515 NM_000265 NP_000256
Function NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). {ECO:0000269|PubMed:19801500, ECO:0000269|PubMed:2547247, ECO:0000269|PubMed:2550933}.
Subcellular Location Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity Detected in peripheral blood monocytes and neutrophils (at protein level). {ECO:0000269|PubMed:2547247, ECO:0000269|PubMed:2550933}.
Top Pathways Leukocyte transendothelial migration, Fc gamma R-mediated phagocytosis, Chemokine signaling pathway, Leishmaniasis, Phagosome

p47-phox CRISPR/Cas9 KO Plasmid (h) - sc-417916 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox HDR Plasmid (h) - sc-417916-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox Double Nickase Plasmid (h) - sc-417916-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox Double Nickase Plasmid (h2) - sc-417916-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox CRISPR Activation Plasmid (h) - sc-417916-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox CRISPR Activation Plasmid (h2) - sc-417916-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox Lentiviral Activation Particles (h) - sc-417916-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox Lentiviral Activation Particles (h2) - sc-417916-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

p47-phox siRNA (h) - sc-29422 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

p47-phox shRNA Plasmid (h) - sc-29422-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

p47-phox shRNA (h) Lentiviral Particles - sc-29422-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU109421 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU127961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU109351 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15013 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15013 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NCF1 siRNA (Human) - CRJ8572 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NCF1 (NM_000265.4) - SHH349933 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NCF1(NM_000265.4) - SHR000654 from Creative biogene

Category siRNA
Species Reactivities Human

NCF1 shRNA Plasmid (Human) - CHJ8572 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NCF1 miRNA 3'UTR clone - MiUTR1H-06672 from Creative biogene

Species Reactivities Human
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