Gene Symbol | ARHGAP35 |
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Entrez Gene | 2909 |
Alt Symbol | GRF-1, GRLF1, P190-A, P190A, p190ARhoGAP, p190RhoGAP |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 35 |
Other Description | glucocorticoid receptor DNA binding factor 1|glucocorticoid receptor DNA-binding factor 1|glucocorticoid receptor repression factor 1|rho GAP p190A|rho GTPase-activating protein 35 |
Swissprots | Q9C0E1 A7E2A4 Q14452 Q9NRY4 |
Accessions | EAW57450 EAW57451 EAW57452 EAW57453 Q9NRY4 AB051509 BAB21813 AF159851 AAF80386 AK096123 AK097314 AK298356 BAG60600 AL831914 BC003514 BC065491 BC131565 AAI31566 BC150257 AAI50258 BE871213 BM855708 CA429690 CX163309 M73077 AAA58618 XM_011526873 XP_011525175 XR_935811 NM_004491 NP_004482 NM_024342 |
Function | Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'- GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor. {ECO:0000269|PubMed:1894621}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton |
p190-A RhoGAP (D8Q6C) Rabbit mAb - 12164 from Cell Signaling Technology
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p190-A RhoGAP Antibody - 2513 from Cell Signaling Technology
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p190-A RhoGAP (C59F7) Rabbit mAb - 2860 from Cell Signaling Technology
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GRF-1 (N-13) - sc-131536 from Santa Cruz Biotechnology
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GRF-1 (C-14) - sc-131534 from Santa Cruz Biotechnology
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GRF-1 (H-200) - sc-367517 from Santa Cruz Biotechnology
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GRF-1 (2389D3a) - sc-81094 from Santa Cruz Biotechnology
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Anti-GRLF1 (phospho Y1087) antibody - ab203274 from Abcam
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Anti-GRLF1 (phospho Y1087) antibody - ab138355 from Abcam
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Anti-GRLF1 (phospho Y1105) antibody - ab182636 from Abcam
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Anti-GRLF1 (phospho Y1105) antibody - ab195833 from Abcam
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Anti-GRLF1 (phospho Y1105) antibody - ab55339 from Abcam
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Anti-GRLF1 antibody - ab85950 from Abcam
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Anti-GRLF1 antibody - ab134726 from Abcam
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Anti-GRLF1 antibody [2389D3a] - ab58674 from Abcam
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Anti-ARHGAP35 / GRLF1 Antibody - LS-C74014 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody - LS-C66598 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (aa1200-1250) - LS-C125692 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (clone 2389D3a) - LS-C184572 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (phospho-Tyr1087) - LS-C291499 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (aa1071-1120) - LS-C199022 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (clone 2389D3a) - LS-C342854 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (clone 4D4-F8) - LS-C197357 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (phospho-Tyr1087) - LS-C178061 from LifeSpan Bioscience
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Anti-ARHGAP35 / GRLF1 Antibody (aa1032-1081) - LS-C199874 from LifeSpan Bioscience
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