Gene Symbol | ARHGAP35 |
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Entrez Gene | 2909 |
Alt Symbol | GRF-1, GRLF1, P190-A, P190A, p190ARhoGAP, p190RhoGAP |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 35 |
Other Description | glucocorticoid receptor DNA binding factor 1|glucocorticoid receptor DNA-binding factor 1|glucocorticoid receptor repression factor 1|rho GAP p190A|rho GTPase-activating protein 35 |
Swissprots | Q9C0E1 A7E2A4 Q14452 Q9NRY4 |
Accessions | EAW57450 EAW57451 EAW57452 EAW57453 Q9NRY4 AB051509 BAB21813 AF159851 AAF80386 AK096123 AK097314 AK298356 BAG60600 AL831914 BC003514 BC065491 BC131565 AAI31566 BC150257 AAI50258 BE871213 BM855708 CA429690 CX163309 M73077 AAA58618 XM_011526873 XP_011525175 XR_935811 NM_004491 NP_004482 NM_024342 |
Function | Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'- GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor. {ECO:0000269|PubMed:1894621}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton |
Human GRLF1 full length protein - ab132572 from Abcam
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ARHGAP35 / GRLF1 Antibody Blocking Peptide - LS-E12377 from LifeSpan Bioscience
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GRLF1 Blocking Peptide - 33R-8106 from Fitzgerald
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GRLF1 Blocking Peptide - abx062697 from Abbexa
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GRLF1 / GRF1 - H00002909-P01-10 from Acris Antibodies
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GRLF1 / GRF1 - H00002909-P01-25 from Acris Antibodies
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Recombinant Human ARHGAP35, His-tagged - ARHGAP35-26370TH from Creative Biomart
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GRLF1 (pY1087) Blocking Peptide - CBP1503 from Cohesion Biosciences
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p-GRF-1 (Y1105) Peptide - BS4232P from Bioworld Technology
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p-GRF-1 (Y1087) Peptide - BS4814P from Bioworld Technology
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Recombinant Human Rho GTPase-activating protein 35(ARHGAP35) ,partial - CSB-YP882093HU CSB-EP882093HU CSB-BP882093HU CSB-MP882093HU from Cusabio
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Recombinant Human p190RhoGAP Protein - H00002909-P01 from Novus Biologicals
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GRLF1 fusion protein - Ag25353 from Proteintech Group
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p190RhoGAP Recombinant Protein Antigen - NBP2-49172PEP from Novus Biologicals
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p190RhoGAP Recombinant Protein Antigen - NBP2-49229PEP from Novus Biologicals
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Phospho-ARHGAP35Y1105-Blocking-Peptide - BP3903a from Abgent, a WuXi AppTec company
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ARHGAP35 Peptide, Human - M34GP00864H from Creative Peptides
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Rho GTPase-activating protein 35 (ARHGAP35), partial, Recombinant Protein - MBS1294606 from MyBioSource
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