Gene Symbol | ARHGAP35 |
---|---|
Entrez Gene | 2909 |
Alt Symbol | GRF-1, GRLF1, P190-A, P190A, p190ARhoGAP, p190RhoGAP |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 35 |
Other Description | glucocorticoid receptor DNA binding factor 1|glucocorticoid receptor DNA-binding factor 1|glucocorticoid receptor repression factor 1|rho GAP p190A|rho GTPase-activating protein 35 |
Swissprots | Q9C0E1 A7E2A4 Q14452 Q9NRY4 |
Accessions | EAW57450 EAW57451 EAW57452 EAW57453 Q9NRY4 AB051509 BAB21813 AF159851 AAF80386 AK096123 AK097314 AK298356 BAG60600 AL831914 BC003514 BC065491 BC131565 AAI31566 BC150257 AAI50258 BE871213 BM855708 CA429690 CX163309 M73077 AAA58618 XM_011526873 XP_011525175 XR_935811 NM_004491 NP_004482 NM_024342 |
Function | Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'- GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor. {ECO:0000269|PubMed:1894621}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton |
GRF-1 CRISPR/Cas9 KO Plasmid (h) - sc-407290 from Santa Cruz Biotechnology
|
||||||||
GRF-1 HDR Plasmid (h) - sc-407290-HDR from Santa Cruz Biotechnology
|
||||||||
GRF-1 Double Nickase Plasmid (h) - sc-407290-NIC from Santa Cruz Biotechnology
|
||||||||
GRF-1 Double Nickase Plasmid (h2) - sc-407290-NIC-2 from Santa Cruz Biotechnology
|
||||||||
GRF-1 CRISPR Activation Plasmid (h) - sc-407290-ACT from Santa Cruz Biotechnology
|
||||||||
GRF-1 CRISPR Activation Plasmid (h2) - sc-407290-ACT-2 from Santa Cruz Biotechnology
|
||||||||
GRF-1 Lentiviral Activation Particles (h) - sc-407290-LAC from Santa Cruz Biotechnology
|
||||||||
GRF-1 Lentiviral Activation Particles (h2) - sc-407290-LAC-2 from Santa Cruz Biotechnology
|
||||||||
GRF-1 siRNA (h) - sc-97682 from Santa Cruz Biotechnology
|
||||||||
GRF-1 shRNA Plasmid (h) - sc-97682-SH from Santa Cruz Biotechnology
|
||||||||
GRF-1 shRNA (h) Lentiviral Particles - sc-97682-V from Santa Cruz Biotechnology
|
||||||||
p190RhoGAP RNAi - H00002909-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU146061 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN9701 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9701 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR14344 from Sigma-Aldrich
|
||||||||
ARHGAP35 siRNA (Human) - CRH1963 from Cohesion Biosciences
|
||||||||
p190RhoGAP RNAi - H00002909-R02 from Novus Biologicals
|
||||||||
ARHGAP35 - MBS8212179 from MyBioSource
|
||||||||
GRF-1 CRISPR/Cas9 KO Plasmid (h2) - sc-407290-KO-2 from Santa Cruz Biotechnology
|
||||||||
GRF-1 HDR Plasmid (h2) - sc-407290-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human ARHGAP35 (NM_004491.4) - SHH239526 from Creative biogene
|
||||||||
shRNA set against Human GRLF1(NM_004491.4) - SHH105473 from Creative biogene
|
||||||||
Human ARHGAP35 siRNA - orb262465 from Biorbyt
|
||||||||
ARHGAP35 shRNA Plasmid (Human) - CHH1963 from Cohesion Biosciences
|