AIFM2

Gene Symbol AIFM2
Entrez Gene 84883
Alt Symbol AMID, PRG3
Species Human
Gene Type protein-coding
Description apoptosis-inducing factor, mitochondrion-associated, 2
Other Description apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death|apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death|apoptosis-inducing factor 2|p53-responsive gene 3 protein
Swissprots Q63Z39 B3KXI0 Q9BRQ8
Accessions CAE90404 EAW54376 Q9BRQ8 AF337957 AAL73229 AF506757 AAM77596 AI922797 AK027403 BAB55089 AK127353 BAG54492 BC006121 AAH06121 BC023601 AAH23601 BG332787 BP331371 BX537621 CAH56481 DQ893092 ABM84018 DQ896364 ABM87363 NM_032797 NP_116186 NM_001198696 NP_001185625
Function Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest. {ECO:0000269|PubMed:11980907, ECO:0000269|PubMed:12135761, ECO:0000269|PubMed:15958387}.
Subcellular Location Cytoplasm. Mitochondrion outer membrane.
Tissue Specificity Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells. {ECO:0000269|PubMed:12135761}.

AMID CRISPR/Cas9 KO Plasmid (h) - sc-406251 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID HDR Plasmid (h) - sc-406251-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID Double Nickase Plasmid (h) - sc-406251-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID Double Nickase Plasmid (h2) - sc-406251-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID CRISPR Activation Plasmid (h) - sc-406251-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID CRISPR Activation Plasmid (h2) - sc-406251-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID Lentiviral Activation Particles (h) - sc-406251-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID Lentiviral Activation Particles (h2) - sc-406251-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AMID siRNA (h) - sc-72339 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AMID shRNA Plasmid (h) - sc-72339-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AMID shRNA (h) Lentiviral Particles - sc-72339-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AMID RNAi - H00084883-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU124161 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2983 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2983 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13195 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13195

AIFM2 siRNA (Human) - CRJ3663 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AIFM2 - MBS8229607 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AIFM2 (NM_032797.5) - SHH233930 from Creative biogene

Category siRNA
Species Reactivities Human

Human AIFM2 siRNA - orb274164 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AIFM2 shRNA Plasmid (Human) - CHJ3663 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AIFM2 miRNA 3'UTR clone - MiUTR3H-07418 from Creative biogene

Species Reactivities Human
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