MGAT5B

Gene Symbol	MGAT5B
Entrez Gene	146664
Alt Symbol	GnT-IX, GnT-VB
Species	Human
Gene Type	protein-coding
Description	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Other Description	N-acetylglucosaminyl-transferase Vb|N-acetylglucosaminyltransferase IX|alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B|alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B|beta(1,6)-N-acetylglucosaminyltransferase V|glcNAc-T Vb|hGnTVb|mannoside acetylglucosaminyltransferase 5B|mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isoenzyme B
Swissprots	Q76D04 Q96LS2 Q766X5 Q6P3S8 Q6P6B3 Q3V5L5
Accessions	EAW89457 EAW89458 EAW89459 EAW89460 Q3V5L5 AB109185 BAC84969 AB114297 BAD02406 AB235153 BAE44474 AK123189 AW191036 BC036948 BC041577 BC062354 AAH62354 BC063862 AAH63862 BC144361 BC156823 AAI56824 HG509473 HG509474 HG509475 XM_005257065 XP_005257122 XM_006721707 XP_006721770 XM_011524348 XP_011522650 XM_011524349 XP_011522651 XM_011524350 XP_011522652 XM_011524351 XP_011522653 XM_011524352 XP_011522654 XM_011524353 XP_011522655 XM_011524354 XP_011522656 XR_934377 NM_001199172 NP_001186101 NM_144677 NP_653278 NM_198955 NP_945193
Function	Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N- acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. {ECO:0000269|PubMed:12941944, ECO:0000269|PubMed:14617637, ECO:0000269|PubMed:14623122, ECO:0000269|PubMed:16606368, ECO:0000269|PubMed:16857188}.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Predominantly expressed in brain. Expressed in all area of the adult and fetal brain Also expressed at much lower level in testis, spleen and thymus. {ECO:0000269|PubMed:12941944, ECO:0000269|PubMed:14623122}.
Top Pathways	N-Glycan biosynthesis, Other types of O-glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GnT-VB (A-14) - sc-164500 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GnT-VB (Q-16) - sc-164501 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-MGAT5B antibody - ab125403 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-MGAT5B Antibody (aa362-411) - LS-C146265 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-MGAT5B Antibody - LS-C335366 from LifeSpan Bioscience Prices $305.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

MGAT5B Antibody - NBP2-30600 from Novus Biologicals Host Rabbit Clonality Polyclonal

Anti-MGAT5B antibody produced in rabbit - HPA017424 from Sigma-Aldrich Host Rabbit Clonality Polyclonal

Anti -MGAT5B (beta-1,6-N-acetylglucosaminyltransferase, GnT-IX, GnT-VB) - 211992 from USBiological Life Science Host Rabbit Clonality Polyclonal

MGAT5B Polyclonal Antibody - A3549 from ABclonal Prices $200.00, $480.00 Sizes 50 µg, 200 µg Host Rabbit Clonality Polyclonal

MGAT5B antibody - 70R-18502 from Fitzgerald Prices $375.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

MGAT5B Antibody - abx002561 from Abbexa Host Rabbit Clonality Polyclonal

MGAT5B antibody - 16993-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

Anti-MGAT5B, Polyclonal Antibody - 25-A3549 from ARP American Research Products Prices $299.00, $449.00 Sizes 100 µg, 200 µg Host Rabbit Clonality Polyclonal

MGAT5B antibody - STJ24547 from St John's Laboratory Ltd Host Rabbit Clonality Polyclonal

MGAT5B antibody - 16993-1-AP from Proteintech Group Prices $279.00 Sizes con: 42 μg/150μl Host Rabbit Clonality Polyclonal

MGAT5B - A3549 from NeoScientific Prices $480.00 Sizes 200 µg Host Rabbit Clonality Polyclonal

Anti-MGAT5B monoclonal antibody - DCABH-200947 from Creative Diagnostics Host Rabbit Clonality Monoclonal

MGAT5B - MBS129180 from MyBioSource Prices $285.00, $555.00 Sizes 50 µg, 200 µg Host Rabbit Clonality Polyclonal

Mgat5b-antibody-C-terminal-region-AI12995 - AI12995 from Abgent, a WuXi AppTec company Prices $293.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

MGAT5B Antibody - SH-A13594 from Novatein Biosciences Prices $315.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

anti-MGAT5B antibody - A005161 from Biobool Host Rabbit Clonality Polyclonal

Anti-Mgat5b Antibody A08123 - A08123 from Boster Bio Prices $299.00 Sizes 1 Host Rabbit Clonality Polyclonal

MGAT5B Polyclonal Antibody - A13870 from ABclonal Prices $130.00, $220.00, $380.00 Sizes 50 µl, 100 µl, 200 µl Host Rabbit Clonality Polyclonal

MGAT5B, Polyclonal Antibody - MBS7601394 from MyBioSource Prices $265.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MGAT5B Antibody (aa362-411, Biotin) - LS-C452135 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

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