PDCD1

Gene Symbol PDCD1
Entrez Gene 5133
Alt Symbol CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
Species Human
Gene Type protein-coding
Description programmed cell death 1
Other Description programmed cell death protein 1|protein PD-1|systemic lupus erythematosus susceptibility 2
Swissprots O00517 Q8IX89 Q15116
Accessions AAC41700 AAC51774 AAN64003 ABK41899 CBX51254 EAW71298 Q15116 AI928135 AK313848 BAG36577 AY206416 AAO25116 AY238517 AAO63583 AY322430 AAP85379 BC074740 AAH74740 CR988122 U64863 AAC51773 XM_006712573 XP_006712636 XM_006724986 XP_006725049 NM_005018 NP_005009
Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. {ECO:0000269|PubMed:21276005}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways T cell receptor signaling pathway, Cell adhesion molecules (CAMs)

Pdcd-1 (N-19) - sc-10295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pdcd-1 (N-19): sc-10295. Western blot analysis of human recombinant Pdcd-1 fusion protein.

Pdcd-1 (C-16) - sc-10298 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pdcd-1 (C-16): sc-10298. Western blot analysis of Pdcd-1 expression in Ramos (A), NAMALWA (B) and U-698-M (C) whole cell lysates.

Pdcd-1 (V-15) - sc-10297 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pdcd-1 (V-15): sc-10297. Western blot analysis of Pdcd-1 expression in NFS-5 C-1 whole cell lysate.

Anti-PD1 antibody - ab117420 from Abcam

Prices $384.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab117420 staining PD1 in Mouse spleen tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 2.5% serum for 1 hour at 25°C; antigen retrieval was by heat mediation in a citrate buffer pH 6. Samples were incubated with primary antibody (1/100 in blocking buffer) for 12 hours at 4°C. An undiluted HRP-conjugated Rabbit anti-goat IgG polyclonal was used as the secondary antibody.See Abreview

Anti-PD1 antibody - ab92484 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab92484, at 10 µg/ml, staining PD1 in formalin fixed, paraffin embedded Human small intestine tissue by Immunohistochemistry.

Anti-PD1 antibody - ab36151 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-PD1 antibody (ab36151) at 2 µg/ml + Human Bone Marrow lysate (35ug protein in RIPA buffer).

Anti-PD1 antibody - ab89828 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PD1 antibody (ab89828) at 1 µg/ml + human stomach tissue lysate at 50 µgdeveloped using the ECL technique

Anti-PD1 antibody - ab183641 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PD1 antibody (ab183641) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-PD1 antibody - ab184191 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PD1 antibody (ab184191) at 1/1000 dilution + NCI-H929 whole cell lysate at 30 µg

Anti-PD1 antibody [EPR4877(2)] - ab137132 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4877(2)
Overlay histogram showing HeLa cells stained with ab137132 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab137132, 1/100 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-PD1 antibody [J116] - ab140950 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone J116
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labelling PD1 with ab140950 at 20 µg/ml.

Anti-PD1 antibody [J116] - Low endotoxin, Azide free - ab171267 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone J116
Flow cytometric analysis of human PD1-transfected cells (right histogram) labeling PD1 with ab171267 (left panel: FITC, right panel: PE) compared to isotype controls (open histograms). Total viable cells were used for analysis.

Anti-PD1 antibody [MIH4] (FITC) - ab110177 from Abcam

Prices $185.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone MIH4

Anti-PD1 antibody [NAT105] - ab52587 from Abcam

Prices $404.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NAT105
Paraffin-embedded human tonsil section stained with ab52587 PD1 antibody at 1/50 dilution.

Anti-PDCD1 / CD279 / PD-1 Antibody (clone J116) IHC-plus™ - LS-B7883 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone J116
Anti-CD279 / PD-1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7883 dilution 20 ug/ml.

Anti-PDCD1 / CD279 / PD-1 Antibody (clone EH12.2H7) - LS-C40800 from LifeSpan Bioscience

Prices $225.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone EH12.2H7
PHA-stimulated (day-3) human peripheral blood lymphocytes stained with purified EH12.2H7, followed by anti-mouse IgG FITC

Anti-PDCD1 / CD279 / PD-1 Antibody (clone MIH4, RPE) - LS-C58041 from LifeSpan Bioscience

Prices $350.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone MIH4
Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD279: RPE.

Anti-PDCD1 / CD279 / PD-1 Antibody (Extracellular Domain, CF) - LS-C74202 from LifeSpan Bioscience

Prices $605.00
Sizes 100 tst
Host Goat
Clonality Polyclonal

Anti-PDCD1 / CD279 / PD-1 Antibody (PE) - LS-C62961 from LifeSpan Bioscience

Prices $245.00
Sizes 50 µg
Host Hamster
Clonality Polyclonal

Anti-PDCD1 / CD279 / PD-1 Antibody (Extracellular Domain) - LS-C74201 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PDCD1 / CD279 / PD-1 Antibody (Extracellular Domain, PE) - LS-C74203 from LifeSpan Bioscience

Prices $605.00
Sizes 100 tst
Host Goat
Clonality Polyclonal

Anti-PDCD1 / CD279 / PD-1 Antibody (clone MIH4) - LS-C74204 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MIH4

Anti-PDCD1 / CD279 / PD-1 Antibody (clone MIH4, PE) - LS-C74206 from LifeSpan Bioscience

Prices $455.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone MIH4

Anti-PDCD1 / CD279 / PD-1 Antibody (clone J43, Biotin) - LS-C106374 from LifeSpan Bioscience

Prices $235.00, $275.00, $475.00
Sizes 50 µg, 100 µg, 500 µg
Host Hamster
Clonality Monoclonal
Clone J43

Anti-PDCD1 / CD279 / PD-1 Antibody (C-Terminus) - LS-C121278 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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