PDCD1

Gene Symbol	PDCD1
Entrez Gene	5133
Alt Symbol	CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
Species	Human
Gene Type	protein-coding
Description	programmed cell death 1
Other Description	programmed cell death protein 1|protein PD-1|systemic lupus erythematosus susceptibility 2
Swissprots	O00517 Q8IX89 Q15116
Accessions	AAC41700 AAC51774 AAN64003 ABK41899 CBX51254 EAW71298 Q15116 AI928135 AK313848 BAG36577 AY206416 AAO25116 AY238517 AAO63583 AY322430 AAP85379 BC074740 AAH74740 CR988122 U64863 AAC51773 XM_006712573 XP_006712636 XM_006724986 XP_006725049 NM_005018 NP_005009
Function	Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. {ECO:0000269|PubMed:21276005}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	T cell receptor signaling pathway, Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human PD1 (biotinylated ) protein fragment - ab190787 from Abcam Category Protein Source HEK 293 cells Species Human

Active human PD1 protein fragment - ab174035 from Abcam Category Protein Prices $428.00 Sizes 100 µg Source HEK 293 cells Species Human

Active human PD1 protein fragment - ab198774 from Abcam Category Protein Prices $911.00 Sizes 100 µg Source HEK 293 cells Species Human

Active mouse PD1 protein fragment - ab180051 from Abcam Category Protein Prices $357.00 Sizes 100 µg Source HEK 293 cells Species Mouse

Human PD1 protein fragment - ab114177 from Abcam Category Protein Source Wheat germ Species Human

Human PD1 protein fragment - ab180060 from Abcam Category Protein Source HEK 293 cells Species Human

Human PD1 protein fragment - ab190415 from Abcam Category Protein Source E. coli Species Human

Human PD1 protein fragment - ab198777 from Abcam Category Protein Source HEK 293 cells Species Human

PD1 peptide - ab173374 from Abcam Category Peptide

PDCD1 / CD279 / PD-1 Antibody Blocking Peptide - LS-E25876 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDCD1 / CD279 / PD-1 Antibody Blocking Peptide - LS-E30321 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PDCD1 / CD279 / PD-1 Antibody Blocking Peptide - LS-E30322 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human PD-1 Protein - H00005133-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PD-1 Protein - H00005133-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PD-1 Blocking Peptide - NBP1-77276PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PD-1 Blocking Peptide - NBP1-77277PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human PD-1 Protein - H00005133-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

PD1 blocking peptide - GTX89528-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human PD-1 Fc Chimera, CF - 1086-PD-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Cynomolgus PD-1, CF - 8509-PD-050 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived, Leu25-Gln167, with a C-terminal 6-His tag

Human PD1 Fc His tag protein - orb83090 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human PDCD1 protein - orb180381 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Canine CD279 (Fc Tag) protein - orb179724 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Cells

Human PD1 His tag protein - orb83091 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Canine CD279 (His Tag) protein - orb179725 from Biorbyt Category Protein Prices $400.00, $434.00 Sizes 50 μg, 100 μg Source Human Cells

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